香港科技大学 - The Hong Kong University of Science and Technology
我的母校,算比较pp的,其中EMBA全球排名很靠前,贴一下新浪上的介绍,大家有什么问题欢迎跟帖提出.[attach]4424[/attach]
[attach]4425[/attach]
[quote]现任校长：朱经武
官网：[url=http://www.ust.hk]http://www.ust.hk[/url]
香港科技大学（下称"科大")位于九龙半岛东侧风景秀丽宜人的清水湾畔。依山临海，在喧嚣的繁华闹市之隙，为莘莘学子提供着一方静雅而辽阔的学术空间。创校15年，已在国际学术界崭露头角。香港科大的迅速崛起，在世界高等教育发展史上演绎了一段颇为独特的传奇.
香港科技大学是一所高度国际化的研究型大学，由理、工、工商管理及人文社会科学四所学院组成。理、工、商学院提供本科生及研究生课程；人文社科学院主要开办研究生课程，同时亦为本科生提供通识教育，以利全面发展。 作为一所高度国际化的研究型大学，科大所有课程均以英语教授 (人文社会科学学院部分关于中国的课程除外)。
科大拥有一支享誉国际的优秀教研队伍。教授、副教授、及助理教授人数共约450名，来自全球35个国家，各级教授全部拥有博士学位，其中75%的教授是从北美62所一流研究型学府取得博士学位。
倾力支持香港科技大学在内地的拓展并尽快取得全球学术领袖地位，霍英东基金会於2005年7月慷慨捐赠8亿港元。此项捐款是科大创校以来最大的一笔私人赞助。
科大无疑是世界上最美丽的大学之一。优越的环境、舒适的宿舍、完善的设施、丰富的活动，令校园生活多姿多彩，成为人生难忘的一段经历。
[align=left][b]国际声誉[/b][/align] 科大自1991年创校以来，已迅速成为国际知名学府。
生物化学系主任叶玉如教授于2004年获颁有"女性诺贝尔奖"之称的"L'OREAL．联合国教科文组世界杰出女科学家成就奖"。
电机及电子工程学系于国际电机电子工程学会"Transactions on Electron Device"学术期刊所发表之研究著作数目，持续高企，于1998-2000年更为世界第一。
机械工程学系在2000-2003年刊登的研究论文平均数目位居全球前三位，与斯坦福大学、加州理工学院相若。
工业工程及工程管理学系于2003-2004年在权威期刊刊登的研究论文数目居全球前四位，与美国哥伦比亚大学、加州大学柏克莱分校相若。
化学工程学系于2000-2003年间在SCI刊登的研究论文平均数介于加州理工学院及麻省理工学院之间，位居世界第四。
商学院与美国西北大学凯洛格管理学院合办的行政人员工商管理硕士课程(EMBA)在2004年《金融时报》排名榜中位列全球第六。
商学院所提供的工商管理硕士课程(MBA)及为企业特设的行政人员课程，在《金融时报》排名榜均位列亚太之首。
商学院是亚洲首家获得两所国际顶级认可机构"美国工商管理学院国际协会"及"欧洲管理教育素质改进系统"双重认证的商学院。
理学院的科学家成功发展了分子生物感受器，并用于监测细胞雕亡过程；研制了全新的电流变液，可供制造离合器，取代齿轮转动装置，为汽车等机械工业带来重大的技术进步。
商学院的会计学研究学术论文总量居全球榜首、经济及金融财务研究亚太称冠。
人文社会科学学院在三份最权威的中国研究学术期刊中发表的论文总数，与哈佛大学和斯坦福大学名列全球首五名。
科大拥有多项亚洲独一无二的大型科研设施，重要设施包括：
亚太院校首个超大型岩土离心机实验所及首个风洞设施 「中电风洞实验所」；
[align=left][b]学生宿舍[/b][/align] 科大将最好的景致留给了学生宿舍，六座学生宿舍全部背山面海，不仅景色优美，住宿条件亦无与伦比。定期举行的各项活动更为入住学生提供了一个相互沟通，拓展兴趣，展示才华的广阔空间。
运动及文康设施
青山，绿水是科大得天独厚的自然环境，科大亦提供了一系列的室内及户外设施满足学生不同的兴趣及需要。
[align=left][b]全面素质培养[/b][/align] 科大提供多元化节目及活动，让学生增进知识及体验丰盛人生。 艺术中心定期举办各项艺术及文化活动，并通过驻校艺术家计划，让学生有机会接触各样艺术和文化活动。 积极开展学生体育及康乐活动，并特别开办“活力生活”课程，令学生全面发展。
导师计划及实习机会可指导学生自我设计未来的发展方向，为就业做准备。
讲座、论坛、卓贤汇，学生们可拓宽视野，提升各项技能，以助个人发展。
国际学术交流活动及各类学生文化交流计划充分增强学生的国际经验。
[align=left][b]学生会及学生组织[/b][/align] 香港科技大学学生会是一个独立的组织，在推动及统筹校内超过100个学生组织所举办的活动方面，担当重要角色。另外，在校的内地本科同学自发成立“中国内地学生学者联谊会本科生部”，为内地同学提供重要的资讯和必要的帮助。
[align=left][b]工商管理学院介绍[/b][/align]香港科技大学工商管理学院（香港科大商学院）成立仅十余年，已成为亚洲首屈一指的商学院。成长之快，无论以哪一个标准看，都可以说是创下先例。与之成长相伴的是科大商学院的成就得到学术界广泛尊重与肯定，赢得国际声誉。高度的学术评价不单使商学院成为本地学生升学的首选，也吸引愈来愈多海外学生，名扬海外。香港科大商学院现已挤身于世界最优秀商学院之列。
2005 财务研究亚太第一 亚利桑那州大学
2005 商学院研究亚太第一 得克萨斯(达拉斯)大学
2005 全日制工商管理硕士(MBA)课程排名全球44位 《金融时报》
2004 科大商学院与美国西北大学Kellogg管理学院合办的EMBA课程排名全球第6位《金融时报》
2003-05 商学院研究全球排名首25位《金融时报》
2003-04 行政人员教育排名 (特设课程) 亚洲及澳洲之冠《金融时报》
2003 EMBA排名全球第9位《金融时报》
2001-03 全日制工商管理硕士排名亚太之首《金融时报》
2003 经济研究亚太第一《欧洲经济协会期刊》
2002 财务研究亚太第一《财务管理》
2000-01 于最权威五份会计期刊的会计研究创作量，排名全球第一《会计研究期刊》、《会计及经济期刊》、《会计学评论》、《现代会计研究》及《会计研究评论》
2001 财务研究亚太第一《太平洋盘地财务期刊》
2000 获欧洲管理教育素质改进系统认证
1999 经济研究亚太第一《经济探研》；获美国工商管理学院国际协会认证
国际排名
近年来，香港科大商学院已取得了骄人的学术成就，在研究和课程质量这两方面成绩尤为突出。
香港科大商学院在各学科研究领域的成就，保证了它的教学内容与时俱进。这些学科包括：会计、经济、经济及财务、财务、计量财务、环球商业管理、综合商业管理、资讯系统、营运管理、组织管理、市场学、科技及管理。[/quote]
[url]http://bbs.edu.sina.com.cn/treeforum/App/view.php?bbsid=55&subid=4&tbid=1360&fid=30676&id=17015[/url]
系里的Faculty
position name e-mailHead Prof Xiao Yuan LI [email]chxyli@ust.hk[/email]
Professor Prof Chi Kwong CHANG [email]chang@ust.hk[/email]
Professor Prof Wei Min DAI [email]chdai@ust.hk[/email]
Professor Prof Richard Kingston HAYNES [email]haynes@ust.hk[/email]
Professor Prof Guochen JIA [email]chjiag@ust.hk[/email]
Professor Prof Zhenyang LIN [email]chzlin@ust.hk[/email]
Professor Prof Reinhard RENNEBERG [email]chrenneb@ust.hk[/email]
Professor Prof Ben Zhong TANG [email]tangbenz@ust.hk[/email]
Professor Prof Yun-Dong WU [email]chydwu@ust.hk[/email]
Professor Prof YiJing YAN [email]yyan@ust.hk[/email]
Professor Prof Shihe YANG [email]chsyang@ust.hk[/email]
Associate Professor Dr Zhi Hong GUO [email]chguo@ust.hk[/email]
Associate Professor Dr Wa Hung LEUNG [email]chleung@ust.hk[/email]
Associate Professor Dr Ian WILLIAMS [email]chwill@ust.hk[/email]
Associate Professor Dr Bing XU [email]chbingxu@ust.hk[/email]
Associate Professor Dr Jian Zhen YU [email]chjianyu@ust.hk[/email]
Assistant Professor Dr Hong Kai WU [email]chhkwu@ust.hk[/email]
Assistant Project Manager Dr Lam Lung YEUNG [email]chyeungl@ust.hk[/email]
Research Assistant Professor Dr Jacky Wing Yip LAM [email]chjacky@ust.hk[/email]
Emeritus Professor Prof H. HIRAOKA [email]chhiraok@.ust.hk[/email]
Emeritus Professor Prof Nai-Teng YU [email]chyu@ust.hk[/email]
Adjunct Professor Prof Chun-Tao CHE
Adjunct Professor Prof Todd Benjamin MARDER
Adjunct Associate Professor Dr Paul R. CARLIER [email]pcarlier@vt.edu[/email]
Adjunct Associate Professor Dr Terence See-Ming WAN
Adjunct Associate Professor Dr Lam-Lung YEUNG [email]chyeungl@ust.hk[/email]
[url]http://www-chem.ust.hk/faculty.htm[/url]
[[i] 本帖最后由 Metalcarbene 于 2007-11-16 12:13 编辑 [/i]]
Professor and Head of Chemistry, Xiao-Yuan LI
[attach]4426[/attach]Professor and Head of Chemistry, Xiao-Yuan LI (Ph.D, M.A., Princeton; B.Sc., Peking )
E-mail: "chxyli@ust.hk"
Tel: (852) 2358-7356; Fax: (852) 2358-1594
Research Interests:
Bio-physical, Bio-analytical, and Bio-inorganic Chemistry;
Biomedical/Analytical Applications of Nanomaterials and Films.
The primary interest of Dr. Li's group is in the chemistry problems derived from biological and life sciences. A new area of research in the group is the functional nanomaterials and their films. The research objectives are approached from the following directions:
BIO-PHYSICAL: we study the synthetic models and the native metalloenzymes by laser-based spectroscopies, especially resonance Raman spectroscopy (RRS) and time-resolved spectroscopy (TRS), aiming at the identification of the functionally important electronic and vibrational motions as well as intermolecular interactions; the interpretation of spectroscopic observables is often assisted by computational modelling at ab initio, semiempirical and molecular mechanics levels;
BIO-ANALYTICAL: we develop electrochemically-based and optically-based microprobes for the molecule-specific detection at cellular and tissue levels, and for
biomedical/clinical applications;
BIO-INORGANIC: we design, synthesize and characterize structural analogs of the functional sites of various metalloproteins, aiming at the understanding of the structural and mechanistic aspects of certain enzymatic functions;
BIO-MIMETIC CATALYSTS: we design, synthesize and characterize practically viable biomimetic catalysts or ''chemzymes'', aiming at applications in bench synthesis and industrial processes.
FUNCTIONAL NANOMATERIALS AND FILMS: We synthesize, characterize and explore applications of functional nanomaterials and their films in bioanalytical and biophysical chemistry.
[url]http://www-chem.ust.hk/faculty_XiaoYuanLi.html[/url]
Professor Chi Kwong CHANG
[attach]4427[/attach]Research Interests:
Organic and bioinorganic chemistry
Research in this laboratory emphasizes the application of synthetic organic methods to construct enzyme analogs and models suitable for detailed mechanistic studies. Our efforts focus on the porphyrin and metalloporphyrin chemistry.
The role of the iron-porphyrin (heme) group among hemoproteins ranges from oxygen binding to drug detoxification. Variations in heme functions can be brought about by axial ligand, steric and environmental effects. These effects can be tested and amplified individually by using suitable synthetic model compounds. Through the study of models, we may understand the underlying principles and help design useful catalysts.
Porphyrin also has a medical application. Some porphyrins when introduced into the human body can accumulate preferentially in rapidly dividing cells (such as cancer). Since porphyrins are also good photosentizers, the combination of light and porphyrin can bring about a cytotoxic effect to selectively eradicate cancerous tissue. We are interested in the design and synthesis of porphyrin-based photosensitizers efficacious for the so-called photodynamic therapy (PDT).
Representative Publications
"Molecular and Crystal Structure of a Binuclear m-Acetato Coupled ZnN3-Zn Porphyrin, N3=Di(2-picolyl)amine: Synthetic Approach to Model the Cytochrome c Oxidase Active Site" Inorg. Chem., 34, 753 (1995).
"Conformational Control of Intramolecular H-Bonding in Heme Models: Maximal Co(II)-O2 Binding in a C-Clamp Porphyrin" J. Am. Chem. Soc., 117, 4191 (1995).
"Synthesis and Structure of N, N’-Bridged Porphycene" J. Chem. Soc. Chem. Commun., 1173 (1995).
"Phenylpyrroles by Suzuki Cross Coupling and a Synthesis of Type I Tetramethyltetraphenylporphyrin" J. Org. Chem. 60, 7030 (1995).
"The Amidinium-Carboxylate Salt Bridge as a Proton-coupled Interface to Electron Transfer Pathways" Angew. Chem. Int. Ed. Engl. 36, 2124 (1997).
[url]http://www-chem.ust.hk/faculty_ChiKwongCHANG.html[/url]
Professor Wei-Min DAI
[attach]4428[/attach]Prof. Wei-Min DAI, Professor of Chemistry
PhD (Kyoto University, Japan, 1990)
MSc (Shanghai Institute of Organic Chemistry, China, 1984)
BSc (Hangzhou University, China, 1982)
Mailing Address:
Department of Chemistry
The Hong Kong University of Science and Technology
Clear Water Bay, Kowloon
Hong Kong SAR, China
E-mail: [email]chdai@ust.hk[/email]
Tel. +852-23587365; Fax: +852-23581594
Research Interests
Synthetic organic and bioorganic chemistry
Prof. Dai's research focuses on two directions: asymmetric catalysis and synthesis, and synthetic studies on bioactive natural products and designed molecules including combinatorial synthesis.
Our contribution in asymmetric catalysis and synthesis includes: (1) development of indole-containing chiral molecules from abrine, and application for enantioselective alkylation of aldehydes with diethylzinc; (2) asymmetric Wittig-type olefinations of chiral arsonium ylides with 4-substituted cyclohexanones and N,N-dialkyl 2-formyl-1-naphthamides; (3) highly diastereoselective desymmetrization of cyclic meso anhydrides using enantiomerically pure 2-substituted N,N-dialkyl 1-naphthamides; (4) remote axial-to-central chirality transfer in enantioselective SmI2-mediated reductive coupling of aldehydes; and (5) Pd-catalyzed asymmetric allylic alkylation (AAA), asymmetric Heck reactions, and asymmetric Suzuki reactions using novel atropisomeric amide-derived phosphines (A2phos), C2-symmetric chiral arsines, and P-chiral secondary phosphine oxides, respectively.
Our accomplishment on synthesis of bioactive molecules covers: (1) the second total synthesis of amphidinolide Y via a RCM approach toward formation of the (E)-trisubstituted double bond embedded within a 17-membered ring; (2) synthesis of the C13–C25 fragment of 24-demethylbafilomycin C1 of the plecomacrolide antibiotics via a diastereoselective ketone aldol reaction; (3) establishment of an allylic rearrangement strategy for in situ formation of 10-membered ring enediynes with promising DNA cleavage and anticancer activity; (4) development of a number of synthetic methodologies for diversity-oriented synthesis of heterocycles from 2-aminophenols via microwave-assisted multi-component reactions and post annulation; (5) demonstration of an integrative approach of microwave-assisted solid phase organic synthesis (MASPOS) with encoded split-pool combinatorial synthesis (ESPCS) as illustrated in Cu-mediated heteroannulation for synthesis of indoles and the first introduction of the cat∙linker concept for promoting on-resin reactions.
Selected Ongoing Projects:
* Total synthesis of macrolactone natural products; [project info in Chinese: SIOC, NSFC, CAS, ZJU, ZJU(2), ZJU(3)]
* Development of novel axially chiral amide-based P,O-ligands and chiral arsines for enantioselective catalysis;
* Asymmetric Wittig-type reactions using chiral arsonium ylides;
* Diversity-oriented synthesis of heterocycles;
* Solid phase organic synthesis;
* Microwave-assisted solid-phase organic synthesis (MASPOS).
Selected Journal Publications: [see more entries]
Total Synthesis:
* Total synthesis of amphidinolide Y by formation of trisubstituted (E)-double bond via ring-closing metathesis of densely functionalized alkenes: Org. Lett. 2007, 9, 2585-2588. [DOI: 10.1021/ol0710360]
* Synthesis of C13–C25 fragment of 24-demethylbafilomycin C1 via diastereoselective aldol reactions of a ketone boron enolate as the key step: J. Org. Chem. 2007, 72, 4953–4960. [DOI: 10.1021/jo070624o]
* A new synthesis of tetrahydrofuran fragment of amphidinolides X and Y: Synlett 2006, 1177–1180. [DOI: 10.1055/s-2006-932487]
* Structures and total syntheses of the plecomacrolides: Curr. Med. Chem. 2005, 12, 1947–1993. [DOI: 10.2174/0929867054546591]
Microwave-Assisted Solid-Phase Organic Synthesis (MASPOS):
* An engineered linker capable of promoting on-resin reactions for microwave-assisted solid-phase organic synthesis: Angew. Chem. Int. Ed. 2006, 45, 7255–7258. [DOI: 10.1002/anie.200602523]
* Microwave-assisted solid-phase organic synthesis (MASPOS) as a key step for an indole library construction: Org. Lett. 2003, 5, 2919–2922. [DOI: 10.1021/ol0350543]
Microwave-Assisted Diversity-Oriented Heterocycle Synthesis:
* Lewis acid-catalyzed formation of Ugi four-component reaction product from Passerini three-component reaction system without an added amine: Tetrahedron 2007, 63, 12866–12876. Available online 16 October 2007. [10.1016/j.tet.2007.10.050]
* Microwave-assisted, palladium-catalyzed intramolecular direct arylation for the synthesis of novel fused heterocycles: Synlett 2007, 2728–2732. [DOI: 10.1055/s-2007-991053]
* Diversity-oriented synthesis and solid-phase organic synthesis under controlled microwave heating: Comb. Chem. High Throughput Screening 2007, 10, accepted for the special issue on "Microwaves in High Throughput Synthesis".
* Unexpected epimerization and stereochemistry revision of IMDA adducts from sorbate-related 1,3,8-nonatrienes: Tetrahedron Lett. 2007, 48, 6543–6547. [DOI: 10.1016/j.tetlet.2007.07.046]
* Isolation and characterization of 2-alkylaminobenzo furans. Evidence for competing O-arylation in Cu-catalyzed intramolecular amidation: Tetrahedron Lett. 2007, 48, 401–404. [DOI: 10.1016/j.tetlet.2006.11.084]
* Microwave-assisted tandem Wittig-intramolecular Diels-Alder cycloaddition. Product distribution and stereochemical assignment: Tetrahedron 2006, 62, 8360–8372. [DOI: 10.1016/j.tet.2006.06.039]
* Microwave-assisted one-pot U-4CR and intramolecular O-alkylation toward heterocyclic scaffolds: Tetrahedron 2006, 62, 6774–6781. [DOI: 10.1016/j.tet.2006.05.001]
* C–N bond-linked conjugates of dibenz[b,f][1,4]oxazepines with 2-oxindole: Synlett 2006, 2099–2103. [DOI: 10.1055/s-2006-948172]
Chirality & Asymmetric Catalysis:
* Efficient remote axial-to-central chirality transfer in enantioselective SmI2-mediated reductive coupling of aldehydes with crotonates of atropisomeric 1-naphthamides: J. Org. Chem. 2006, 71, 2445–2455. [DOI: 10.1021/jo0526486]
* A novel class of nonbiaryl atropisomeric P,O-ligands for palladium-catalyzed asymmetric allylic alkylation: Org. Lett. 2002, 4, 1615–1618. [DOI: 10.1021/ol0258233]
Designed Enediyne Prodrugs:
* Natural product inspired design of enediyne prodrugs via rearrangement of an allylic double bond: Curr. Med. Chem. 2003, 10, 2265–2283. [abstract]
* DNA cleavage potency, cytotoxicity, and mechanism of action of a novel class of enediyne prodrugs: J. Med. Chem. 2002, 45, 758–761. [DOI: 10.1021/jm015588e]
Selected Conference Presentations: [see more entries]
* Invited Talk. "Synthesis of (12Z)-amphidinolide X" Singapore-China Collaborative and Cooperative Chemistry Symposium (SCCCCS-4), Hangzhou, China, 26–27 October 2007.
* Invited Talk. "Total synthesis of anticancer macrolides" Sino-French Workshop on Bioorganic and Medicinal Chemistry (SFWBMC 07), Hangzhou, China, 17–19 October 2007.
* Keynote Talk. "Microwave-assisted MCR and solid-phase reactions for diversity-oriented synthesis of heterocyclic scaffolds" International Symposium on Environmental and Green Chemistry (EGC) 2007 of 12th Asian Chemical Congress (12ACC), Kuala Lumpur, Malaysia, 23–25 August 2007.
* Invited Talk. "Total synthesis of marine natural product amphidinolide Y by using a RCM strategy" 3rd Yoshimasa Hirata Memorial Lecture, Nagoya, Japan, 6 February 2007.
* Invited Talk. "A RCM strategy for synthesis of the tetraene core of the plecomacrolides" The 9th International Symposium for Chinese Organic Chemists (ISCOC-9), Singapore, 17–21 December 2006.
* Invited Talk. "Diversity-oriented solution and solid-phase synthesis of bioactive heterocycle libraries" ICS-UNIDO Workshop on Combinatorial Chemistry and Technologies, Molecular Design and Their Application to Exploit Biodiversity, National Chemical Laboratory, Pune, India, 15–17 December 2006.
Selected PhD Theses: [see more entries]
* Yucui GUAN: "Study toward total synthesis of complex antitumor plecomacrolide 24-demethylbafilomycin C1", June 2007, ZJU, China.
* Xinglong XING: "Microwave-assisted MCR-annulation approaches toward heterocycles synthesis", September 2006, ZJU, China.
* Xuan WANG: "Studies on preparation of aromatic amines and their synthetic and biological applications", August 2005, HKUST. [Abstract]
* Ye ZHANG: "Development of amide-derived P,O-ligands for Suzuki cross-coupling of aryl chlorides and the asymmetric version", August 2005, HKUST [Abstract]
[url]http://ihome.ust.hk/~chdai/[/url]
[[i] 本帖最后由 Metalcarbene 于 2007-11-16 12:26 编辑 [/i]]
Professor Richard K. HAYNES
[b][attach]4429[/attach][/b]
Professor Richard K. HAYNES (PhD, Univ. of Western Australia, 1970)
E-mail: "haynes@ust.hk"
Research Interests:
Drug design, organic synthesis of biologically active natural
products, asymmetric catalysis
Drug Design
Professor Haynes has an ongoing interest in the drug qinghaosu isolated from the Chinese herb qing hao (Artemisia annua). The compound is especially active against multidrug resistant falciparum malaria, and the World Health Organization has a number of programmes aimed at optimizing use of this drug and its derivatives for clinical use against malaria. It is structurally quite different to classical antimalarial drugs such as quinine. The special promise of qinghaosu lies in its potential for use against other diseases. Several derivatives, for example, display pronounced cytotoxic activity. In order to optimize these properties, and thereby prepare new drugs, a wide ranging programme involving collaboration with a large European pharmaceutical company, and with other faculty in the Chemistry and Biology Departments is underway. Activities include the mapping of the mode of action, the preparation of new derivatives, and evaluation of cytotoxicities against a number of cell lines. For example, compounds bearing ligands capable of interacting with DNA have been prepared and will be submitted for in vivo trials against specific tumours. Some six patents have been applied for as a result of new work carried out in the group.
[attach]4430[/attach][attach]4431[/attach]
Organic Synthesis
The group has uncovered a new variation of the Diels-Alder reaction involving the reaction of hexa-3,5-dienols with cyclic enones wherein the trimethylsilyl ethers react at low temperature with cyclic enones to give trans adducts arising via cationic mechanism. The reaction is significant for two reasons. Firstly, it delivers trans-fused bicylic octalins, which is contrary to the normal outcome of a Diels-Alder reaction. Secondly, it has been shown that enantiomerically pure 2-methyl-hexa-3,5-dienols react with racemic enones to deliver adducts as single enantiomers.
he current work is aimed at optimizing the yields of the reactions, and applying it to the synthesis of structurally complex, biologically active natural products.
[attach]4432[/attach]
Asymmetric Catalysis
At the core of this work lies a facile resolution process wherein electrophilic and nucleophilic P-chiral phosphine oxides are obtained in multigram quantities suitable for elaboration into functionalized phosphine oxides. These functionalized phosphine oxides have the potential to serve as ligands in catalysed asymmetric reactions, and to this end, collaborative work involving groups within the Department, and at other universities in Hong Kong is underway. Two key developments have been the uncovering of a completely stereoretentive rearrangement of P-chiral aryl phosphinates to o-hydroarylphosphine oxides and the generation of an electrophilic precursor to P-chiral phosphine sulfides, which in turn will serve as source of P-chiral phosphines, of value in catalysed asymmetric hydrogenation and other reactions.
[attach]4433[/attach]
Representative Publications
"Highly Diastereoselective Conjugate Addition of Lithiated g-Crotonolactone (But-2-en-4-olide) to Cyclic Enones to give Syn-Adducts" J. Org. Chem. 62, 4552 (1997).
'The First Examples of Enantiomerically Pure Diphosphine Dioxides" Chemistry – A European Journal 3, 2052-2057 (1997).
"A Novel Endoperoxide and Related Sesquiterpenes from Artemisia annua derived from Allylic Hydroperoxides" Tetrahedron 54, 4345-4356 (1998).
"Trimethylsilyl Triflate Catalysed Diels-Alder Reaction of TMS Ethers of Conjugated Dienols with Cyclic Enones: Evidence for an Endo Transition State, and First Application to the Synthesis of Enantiopure Octalins" Tetrahedron 55, 89-118 (1999).
[url=http://www-chem.ust.hk/faculty_RichardKHAYNES.html]http://www-chem.ust.hk/faculty_RichardKHAYNES.html[/url]
[[i] 本帖最后由 Metalcarbene 于 2007-11-16 12:33 编辑 [/i]]
Professor Guochen JIA
[attach]4434[/attach]Professor Guochen JIA (PhD, Ohio State, 1989)
E-mail: "chjiag@ust.hk"
Research Interests:
Synthetic inorganic and organometallic chemistry, catalysis
Dr Jia's research involves the design, synthesis, and characterization of inorganic and organometallic compounds with useful properties. Current research projects include: (1) synthesis and properties of conjugated bimetallic and polymeric organometallic materials; (2) design and synthesis of novel ligands and metal complexes for stereoselective synthesis; (3) organometallic chemistry and catalytic properties of s-complexes especially dihydrogen complexes; (4) chemistry of vinylidene, allenylidene carbine and carbyne complexes, metallabenzyes; (5) Reactivity of hydride complexes; and (6) homogeneous catalysis.
Representative Recent Publications (2003-present)
78. Liu, S. H.; Wen, T. B.; Zhou, Z.; Lo, M. F.; Williams, I. D.; Jia, G. "Synthesis and Characterization of Bimetallic Ruthenium Complexes with Linear (CH)6 and related Bridging ligands." Organometallics, 2003, 22, 737-743.
79. Wen,T. B. Ng, S. M.; Hung W. Y., Zhou, Z. Y.; Lo, M. F.; Shek L. Y.; Williams, I. D.; Lin, Z.; Jia, G. "Protonation and Bromination of an Osmabenzyne: Reactions Leading to the Formation of New Metallabenzynes." J. Am. Chem. Soc. 2003, 125,884-885.
80. Liu, S. H.; Huang, X.; Ng, W. S.; Wen, T. B.; Lo, M. F.; Zhou, Z. Y.; Williams, I. D.; Lin, Z.; Jia, G. "A Comparative Study on the Reactivity of H2, PhCH=CH2 and PhCoCMe with [Cp*Ru(H2O)(NBD)]+ ." Organometallics, 2003, 22, 904-906.
81. Ng, S. M. Lam, W. H.; Mak, C. C.; Tsang, C. W.; Jia, G.; Lin, Z.; Lau, C. P. "C-H Bond Activation by a Hydrotris(pyrazolyl)borato Ruthenium Hydride Complex". Organometallics, 2003, 22, 641-651.
82. Hu, Q. Y.; Lo, M. F.; Williams, I. D.; Koda, N.; Uchimarum Y.; Lo, M. F.; Williams, I. D.; Jia, G. "Synthesis and Characterization of Trimetallic Complexes with a Borazine Core".J. Organomet. Chem. 2003, 670, 243-247(invited contribution).
83. Lam, W. H.; Jia, G.; Lau, C. P.; Lin, Z. Y.; Eisenstein, O. "Theoretical studies on the metathesis processes, Tp(PH3)MR(h2-H-CH3) R Tp(PH3)M(CH3)(h2-H-R) (M= Fe, Ru, and Os; R= H and CH3)". Chem. Eur. J. 2003,9, 2775-2782.
84. Jia, G.; Lin, Z. Y.; Lau, C. P. "Reactions of Dihydrogen(norbornadiene) Complexes". Eur. J. Inorg. Chem. 2003, 2551-2562 (invited contribution).
85. Ng, S. M.; Huang, X.; Wen, T. B.; Jia, G.; Z. Lin. "Theoretical Studies on the Stabilities of Metallabenzynes." Organometallics 2003, 22, 3898-3904.
86. Liu, S. H.; Xia, H. P.; Wam, K. L.; Yeung, R. C. Y.; Hu, Q. Y.; Jia, G. "Synthesis of [TpRu(CO)(PPh3)]2(m-CH=CH-CH=CH-C6H4-CH=CH-CH=CH) from Wittig Reactions." J. Organomet. Chem. 2003, 683, 331-336.
87. Wen, T. B.; Zhou, Z. Y.; Lo, M. F.; Williams, I. D.; Jia, G. "Vinylidene, Allenylidene and Carbyne Complexes from the Reactions of [OsCl2(PPh3)3]with HCoCC(OH)Ph2."Organometallics 2003, 22, 5217-5225.
88. Wen, T. B.; Zhou, Z. Y.; Jia, G. "Coupling Reaction of Phenylacetylene with OsHn(PPh3)(2, 6-(PPh2CH2)2C6H3) (n = 1,3)." Organometallics 2003, 22, 4947-4951.
89. Xia, H.; He, G.; Zhang, H.; Wen, T. B.; Sung, H. H. Y.; Williams, I. D.; Jia, G. "Osmabenzenes from the Reactions of HCoCCH(OH)CoCH with OsX2(PPh3)3 (X = Cl, Br)." J. Am. Chem. Soc.2004, 126, 6862-6863.
90. Jia, G. "Progress in the Chemistry of Metallabenzynes."Acc. Chem. Res. 2004, 37, 479 - 486.
91. Wen, T. B.; Hung, W. Y.; Zhou, Z. Y.; Lo, M. F.; Williams, I. D.; Jia, G. "Synthesis and Characterization of [OsCl2(=C=CHR)(PPh3)2] and Related Complexes." Eur. J. Inorg. 2004, 2837-2846.
92. He, G. M.; Xia, H. P.; Jia, G. "Progress in the synthesis and reactivity studies of metallabenzenes." Chin. Sci. Bull. 2004, 49, 1543-1553.
93. Xue, P.; Bi, Z.; Sung, H. H. Y.; Williams, I. D.; Lin, Z.; Jia, G. "Isomerism of [Ru(h3-allyl)Cl(CO)(PPh3)2]." Organometallics, 2004, 23, 4735-4743.
94. Xia, H.; Wen, T. B.; Hu, Q. Y.; Wang, X.; Chen, X. G.; Shek L. Y.; Williams, I. D.; Wong, K. S.; Wong, K. L.; Jia, G. "Synthesis and Characterization of Trimetallic Ruthenium and Bimetallic Osmium Complexes with Metal-vinyl Linkages." Organometallics, 2005, 24, 562-569.
95. Liu, S. H.; Hu, Q. Y.; Xue, P.; Wen, T. B.; Williams, I. D.; Jia, G. "Synthesis and Characterization of C10H-10-Bridged Bimetallic Ruthenium Complexes." Organometallics, 2005, 24, 769-772.
96. Bi, S.; Ariafard, A.; Jia, G.; Lin, Z. "Isomerism of Cp-containing Transition Metal Allyl Complexes." Organometallics, 2005, 24, 680-686.
97. Wen, T. B.; Hung, W. Y.; Sung, H. H. Y.; Williams, I. D.; Jia, G. "Syntheses of Metallabenzynes from an Allenylcarbene Complex." J. Am. Chem. Soc. 2005,127, 127(9); 2856-2857.
98. Yuan, P.; Liu, S. H.; Xiong, W.; Yin, J.; Yu, G.; Sung, H. Y.; Williams, I. D.; Jia, G.; Organometallics,2005, 1452-1457.
[url]http://www-chem.ust.hk/faculty_GuochenJIA.html[/url]
Prof Zhenyang LIN
[attach]4435[/attach]Zhenyang LIN (D.Phil Oxford 1989)
Professor
Department of Chemistry
The Hong Kong University of Science & Technology
Clear Water Bay, Kowloon
Hong Kong
Tel no.: 2358-7379
Email: [email]chzlin@ust.hk[/email]
Research Interests
Theoretical and computational inorganic chemistry:
Structure, bonding and computer modelling in inorganic, organometallic, inorganic cluster and solid state systems. Development and application of theories in the design of catalysts and other useful materials.
A Full List of Research Publications
[url]http://home.ust.hk/~chzlin/research.html[/url]
[url]http://home.ust.hk/%7Echzlin/[/url]
Professor Reinhard RENNEBERG
[attach]4436[/attach]Professor Reinhard RENNEBERG
(PhD, Central Institute of Molecular Biology,Berlin, 1979)
E-mail: "chrenneb (at) usthk.ust.hk"
Biosensor Group
Research Interests:
Analytical biochemistry and biotechnology, biosensorics and bioelectronics, biomedical and environmental chemistry, immobilization of biomolecules and living cells, commercialization of biosensors and biotests
The Biosensor & Bioelectronics Lab is developing novel rapid tests for biomedical and environmental applications. It has formed the SiGNAL network (Sino-German Nano-Analytical Lab) for collaboration within the frame of the German Center, HKUST Europe Institute.
1. Cell sensors for gathering complex information about living cell: the BOD sensor
Living yeast cells (Arxula adeninivorans) are immobilized at the top of Clark oxygen sensors and mass-produced thick-film sensors. Any change in cell respiration can be monitored in 70 seconds. The cells are stable and can be reused for several months. As they are salt-tolerant, one can directly measure the biodegradable pollution in sea water samples within minutes instead of the 5-day-method (BOD5).
2. Enzyme sensors: Fitness sensors for human athletes and horses
Thick-film sensors and thin-film sensors produced by microsystem technology are used as transducers for immobilized lactate oxidase and glucose oxidase. By checking the lactate levels before and after training for humans and horses, one can evaluate fitness levels easily within seconds. It was demonstrated for subcutaneous in-vivo measurements during training.
3. Antibody-based sensors: Fatty-Acid Binding Protein (FABP) sensor for detection of heart infarction and overtraining muscle damage
An optical immunosensor and immunotest detects FABP, which is a 15 kDa muscle protein within one minute. FABP is an early infarction marker and allows diagnosis or exclusion of acute myocardial infarction within half an hour after the event. Conventional markers need 5-6 hours. In addition to the saving lives, the immunosensor can be also used for detection of overtraining in athletes and horses.
4. Sensors using a prosthetic group: cyanide sensor for fighting cyanide fishing in the Pacific Ocean
Cyanide fishing destroys nowadays many coral reefs in the Pacific Ocean. One million kilograms of cyanides have been used in the last 10 years in Pacific coral reefs to catch fishes mainly for consumption in Hong Kong. Using the oxygen binding abilities of porphyrines, a sensor is constructed for highly sensitive detection of cyanide in fish blood. We hope to help to stop cyanide fishing by deveoping a rapid test.
Representative Publications
"Coupled Enzyme Reactions for Novel Biosensors" Trends in Biochem. Sci. 11, 216-220 (1986).
"Fluorimetric Immunosensors" CRC Press N.Y. 1995.
"Micromachined Glucose Sensor" Biosensors & Bioelectronics 11, 187-190 (1996).
"Enzyme-immunosensor for Diagnosis of Myocardial Infarction" Sensors & Actuators, B30, 71-76 (1996).
"Immunosensors for Clinical Diagnostics" in: Frontiers in Biosensors II, Practical Applications. (Scheller, F.W., Schubert, F. and Fedrowitz, J., eds.) Birkhaeuser, Basel 1997.
"Rapid Measurement of Biodegradable Substances in Water using Novel Microbial Sensors" in : "Biosensors and Applications" (Ngo, T.T. and Yang, V.C., eds.) ASI Press 1997.
Advances in Biosensors. Vol 4: A Chinese Perspective" (Turner, APF and Renneberg, R. , eds.) JAI Press Inc. Stamford, Connecticut (1999).
"Novel Microbial sensors for waste water control", In: "Advances in Biosensors. Vol 4: A Chinese Perspective"(Turner, APF and Renneberg, R. , eds.) JAI Press Inc. (1999), 195-213
[url]http://www-chem.ust.hk/faculty_ReinhardRENNEBERG.html[/url]
Prof Ben Zhong TANG
[attach]4437[/attach]Ben Zhong Tang, Ph.D. Professor of Chemistry
Department of Chemistry, The Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China
Phone: +852-2358-7375 (Office), +852-2358-8801 (Lab); Fax: +852-2358-1594 (Office); E-mail: [email]tangbenz@ust.hk[/email]
07/2005-present Professor, Department of Chemistry, The Hong Kong University of Science & Technology, China
07/1994-06/2005 Assistant/Associate Professor, Department of Chemistry, The Hong Kong University of Science & Technology, China
04/1989-06/1994 Postdoctoral Research Associate, University of Toronto, Canada, and Senior Scientist, Central Research Laboratory, Neos Co., Ltd., Shiga, Japan
04/1983-03/1988 MS and Ph.D., Department of Polymer Chemistry, Kyoto University, Japan
02/1978-01/1982 BS, Department of Polymer Science & Engineering, South China University of Technology, China
Research Interest Polymer Chemistry and Materials Science
Exploration of new catalyst systems, development of new polymerization reactions, synthesis of new functional materials, discovery of new natural phenomena, and creation of new scientific knowledge
Academic Honors and Professional Services
* Croucher Senior Research Fellowship Award, Croucher Foundation (2007)
* Wang Baoren Award for Accomplishments in Basic Polymer Research, Chinese Chemical Society (2007)
* Distinguished Young Scholar (for overseas scientists of Chinese origin), National Science Foundation of China (2002)
* Listed as one of the most cited chemists in the Scientist Rankings in Chemistry of ISI with an average citation rate of 15.09 cites/paper (2007)
* Listed as one of the most cited materials scientists in the Scientist Rankings in Materials Science of ISI with an average citation rate of 22.96 cites/paper (2007)
* . Science News Contributor, Noteworthy Chemistry, published by the American Chemical Society
* International Advisory Board Member, Macromolecular Chemistry & Physics, published by Wiley-VCH
* International Advisory Board Member, Journal of Polymer Materials, published by MD Publications Pvt Ltd
* Editorial Board Member, Progress in Polymer Science, published by Elsevier
* Editorial Board Member, Acta Polymerica Sinica, published by the Chinese Chemical Society
* Editorial Board Member, Journal of Inorganic and Organometallic Polymers and Materials, published by Springer
* Editorial Board Member, Journal of Nanoscience and Nanotechnology, published by the American Scientific Publishers
Selected Examples of Recent Publications (for a complete list, click here)
* Acetylenes with Multiple Triple Bonds: a Group of Versatile An-Type Building Blocks for the Construction of Functional Hyperbranched Polymers Polymer 2007, 48, 6181. (invited Feature article)
* Functional Hyperbranched Macromolecules Constructed from Acetylenic Triple-Bond Building Blocks Adv. Polym. Sci. 2007, 209, 1. (invited review article)
* Functional Polyacetylenes Acc. Chem. Res. 2005, 38, 745. (invited review article; recognized as a Most-Cited Article and featured as a Hot Paper)
* Liquid-Crystalline and Light-Emitting Polyacetylenes J. Polym. Sci. Part A: Polym. Chem. 2003, 41, 2607 (invited Highlight article)
Articles
* Sheetlike Side-Chain Liquid Crystalline Polyacetylenes Forming Monolayer Lamellae in Dilute Solutions Macromolecules 2007, 40, 8342.
* Acetylene Polycyclotrimerization: Synthesis and Characterization of Ferrocene-Containing Hyperbranched Polyarylenes Macromolecules 2007, 40, 5612.
* Convenient Attachment of Highly Polar Azo Chromophore Moieties to Disubstituted Polyacetylene through Polymer Reactions by Using "Click" Chemistry Macromolecules 2007, 40, 5634.
* Hyperbranched Poly(ferrocenylphenylenes): Synthesis, Characterization, Redox Activity, Metal Complexation, Pyrolytic Ceramization and Soft Ferromagnetism Macromolecules 2007, 40, 8195.
* Hyperbranched Poly(silylenephenylenes) from Polycyclotrimerization of A2-Type Diyne Monomers: Synthesis, Characterization, Structural Modeling, Thermal Stability, and Fluorescent Patterning Macromolecules 2007, 40, 7473.
* Metal-Free, Regioselective Diyne Polycyclotrimerization: Synthesis, Photoluminescence, Solvatochromism, and Two-Photon Absorption of a Triphenylamine-Containing Hyperbranched Poly(aroylarylene) Macromolecules 2007, 40, 4879.
* Disubstituted Polyacetylenes Containing Photopolymerizable Vinyl Groups and Polar Ester Functionality: Polymer Synthesis, Aggregation-Enhanced Emission, and Fluorescent Pattern Formation Macromolecules 2007, 40, 3159.
* Decorating Conjugated Polymer Chains with Naturally Occurring Molecules: Synthesis, Solvatochromism, Chain Helicity, and Biological Activity of Sugar-Containing Poly(phenylacetylene)s Macromolecules 2007, 40, 2633.
* Synthesis, Thermal Stability, and Linear and Nonlinear Optical Properties of Hyperbranched Polyarylenes Containing Carbazole and/or Fluorene Moieties Macromolecules 2007, 40, 1914.
* Click Polymerization: Facile Synthesis of Functional Poly(aroyltriazole)s by Metal-Free, Regioselective 1,3-Dipolar Polycycloaddition Macromolecules 2007, 40, 2308.
* Metallized Hyperbranched Polydiyne: a Photonic Material with a Large Refractive Index Tunability and a Spin-Coatable Catalyst for Facile Fabrication of Carbon Nanotubes Chem. Commun. 2007, 2584.
* Hybridization of Thiol-Functionalized Poly(phenylacetylene) with Cadmium Sulfide Nanorods: Improved Miscibility and Enhanced Photoconductivity Chem. Commun. 2007, 1322.
* Switching the Light Emission of (4-Biphenylyl)phenyldibenzofulvene by Morphological Modulation: Crystallization-Induced Emission Enhancement Chem. Commun. 2007, 40.
* Aggregation-Induced and Crystallization-Enhanced Emissions of 1,2-Diphenyl-3,4-bis(diphenylmethylene)-1-cyclobutene Chem. Commun. 2007, 3255.
* Fluorescence Enhancements of Benzene-Cored Luminophors by Restricted Intramolecular Rotations: AIE and AIEE Effects Chem. Commun. 2007, 70.
* Correlations between Percolation Threshold, Dispersion State and Aspect Ratio of Carbon Nanotubes Adv. Funct. Mater. 2007, 17, 3207.
* Aggregation-Induced Emissions of Tetraphenylethene Derivatives and Their Utilities as Chemical Vapor Sensors and in Organic Light-Emitting Diodes Appl. Phys. Lett. 2007, 91, 011111.
* Protein Detection and Quantitation by Tetraphenylethene-Based Fluorescent Probes with Aggregation Induced-Emission Characteristics J. Phys. Chem. B 2007, 111, 11817.
* Color-Tunable, Aggregation-Induced Emission of a Butterfly-Shaped Molecule Comprising of a Pyran Skeleton and Two Cholesteryl Wings J. Phys. Chem. B 2007, 111, 2000.
* Aggregation-Induced Emission: Effects of Molecular Structure, Solid-State Conformation, and Morphological Packing Arrangement on Light-Emitting Behaviors of Diphenyldibenzofulvene Derivatives J. Phys. Chem. C 2007, 111, 2287.
* Fabrication of Hexaphenylsilole Nanowires and Their Morphology-Tunable Photoluminescence Chem Phys Chem 2007, 8, 1513.
* Endowing Hexaphenylsilole with Chemical Sensory and Biological Probing Properties by Attaching Amino Pendants to the Silolyl Core Chem. Phys. Lett. 2007, 446, 124.
* . Photo-Cross-Linkable Light-Emitting Polymers for Holographic Patterning Appl. Phys. Lett. 2006, 89, 191109.
* Amorphous Diphenylaminofluorene-Functionalized Iridium Complexes for High-Efficiency Electrophosphorescent Light-Emitting Diodes Adv. Funct. Mater. 2006, 16, 838.
* Wrapping Carbon Nanotubes in Pyrene-Containing Poly(phenylacetylene) Chains: Solubility, Stability, Light Emission, and Surface Photovoltaic Properties Macromolecules 2006, 39, 8011.
* Synthesis, Structural Characterization, and Thermal and Optical Properties of Hyperbranched Poly(aminoarylene)s Macromolecules 2006, 39, 7973.
* Functional Disubstituted Polyacetylenes: Synthesis, Liquid Crystallinity, Light Emission, and Fluorescent Photopatterning of Biphenyl-Containing Poly(1-phenyl-1-octyne)s with Different Functional Bridges J. Phys. Chem. B 2006, 110, 21613.
* Functional Perovskite Hybrid of Polyacetylene Ammonium and Lead Bromide: Synthesis, Light Emission, and Fluorescence Imagining J. Phys. Chem. B 2006, 110, 21701.
* Light-Emitting Polyacetylenes: Synthesis and Electro-optical Properties of Poly(1-phenyl-1-alkyne)s Bearing Naphthyl Pendants Macromolecules 2006, 39, 6997.
* Construction of Hyperbranched Polyphenylenes Containing Ferrocenyl Units by Alkyne Polycyclotrimerization Macromolecules 2006, 39, 6458.
* Fluorescent "Light-Up" Bioprobes Based on Tetraphenylethylene Derivatives with Aggregation-Induced Emission Characteristics Chem. Commun. 2006, 3705.
* Synthesis, Helicity, and Chromism of Optically Active Poly(phenylacetylene)s Carrying Different Amino Acid Moieties and Pendant Terminal Groups J. Phys. Chem. B 2006, 110, 11128.
* Tunable Aggregation-Induced Emission of Diphenyldibenzofulvenes Chem. Commun. 2006, 1133.
* Facile Synthesis, Large Optical Nonlinearity, and Excellent Thermal Stability of Hyperbranched Poly(aryleneethynylene)s Containing Azobenzene Chromophores Macromolecules 2006, 39, 1436. (listed as one of the Most-Cited ACS Journal Articles)
* Synthesis of, Light Emission from, and Optical Power Limiting in, Soluble Single-Walled Carbon Nanotubes Functionalized by Disubstituted Polyacetylenes J. Phys. Chem. B 2006, 110, 2302.
* Functionalization of Disubstituted Polyacetylenes through Polymer Reactions: Syntheses of Functional Poly(1-phenyl-1-alkyne)s Macromolecules 2006, 39, 467.
* . Induced Chain Alignment, Efficient Energy Transfer, and Enhanced Light Emission in Functional Polyacetylene-Perovskite Hybrids Macromolecules 2005, 38, 8127.
* A New Route to Hyperbranched Macromolecules: Syntheses of Photosensitive Poly(aroylarylene)s via Regioselective Polycyclotrimerization of Bis(aroylacetylene)s Macromolecules 2005, 38, 6382.
* Making Silole Photovoltaically Active by Attaching Carbazolyl Donor Groups to the Silolyl Acceptor Core Chem. Commun. 2005, 3583.
* Structural Control of the Photoluminescence of Silole Regioisomers and Their Utility as Sensitive Regiodiscriminating Chemosensors and Efficient Electroluminescent Materials J. Phys. Chem. B 2005, 109, 10061.
* Frustrated Molecular Packing in Highly Ordered Smectic Phase of Side-Chain Liquid Crystalline Polymer with Rigid Polyacetylene Backbone J. Am. Chem. Soc. 2005, 127, 7668.
* Structures, Electronic States, Photoluminescence, and Carrier Transport Properties of 1,1-Disubstituted 2,3,4,5-Tetraphenylsiloles J. Am. Chem. Soc. 2005, 127, 6335.
* Functional Disubstituted Polyacetylenes and Soluble Cross-Linked Polyenes: Effects of Pendant Groups or Side Chains on Liquid Crystallinity and Light Emission of Poly(1-phenyl-1-undecyne)s Macromolecules 2005, 38, 3290.
* From Nonconjugated Diynes to Conjugated Polyenes: Syntheses of Poly(1-phenyl-7-aryl-1,6-heptadiyne)s by Cyclopolymerizations of Asymmetrically a,w-Disubstituted Alkadiynes Macromolecules 2005, 38, 660.
Selected Examples of Invited Talks at Recent Conferences (for a complete list, click here)
* The 234th ACS National Meeting, Boston, MA, 19-23 Aug. 2007.
* The 233rd ACS National Meeting, Chicago, USA, 25-29 Mar. 2007.
* SPIE Photonics West, San Jose, California, USA, 20-25 Jan. 2007.
* SPIE International Symposium on Optics & Photonics, San Diego, USA, 13-17 Aug. 2006.
* The 3rd IUPAC International Symposium on Macro- and Supramolecular Architectures and Materials, Tokyo, Japan, 28 May-1 June 2006.
* The 3rd International Conference on Photoresponsive Organics and Polymers, Val Thorens, France, 15-20 Jan. 2006.
* Pacifichem 2005 Chemical Congress, Honolulu, Hawaii, USA, 15-20 Dec. 2005.
* The 230th ACS National Meeting, Washington, DC, USA, 28 Aug.-1 Sept. 2005.
* The 88th Canadian Chemistry Conference and Exhibition, Saskatoon, Canada, 27 May-1 June 2005.
Teaching Notes
* Chem324/588: Polymer Chemistry
* Chem328/554: Chemistry for Advanced Materials
* Chem391: Chemical Information
* Nano510: Chemistry of Nanomaterials
* Nano601A: Aggregation-Induced Emission
Photo Collections
* Clear Water Bay campus view
* Group photo (27 Jan 2006)
* Group photo (10 Jan 2007)
* Group photo (25 Oct 2007)
[url]http://home.ust.hk/~tangbenz/[/url]
Prof Yun-Dong WU
[attach]4438[/attach]Yun-Dong WU (PhD, Pittsburgh, 1986)
Professor
E-mail: "chydwu@ust.hk"
Research Interests
Theoretical organic and bioorganic chemistry
(1) Design of new catalysts for stereoselective organic synthesis;
(2) Chemistry of early-transition-metal alkyl and alkylidene complexes.
(3) Conformational studies of peptides, and molecular design based on amino acids and analogous.
(4) Protein folding.
Academic Honors and Activities
Overall Publications
Publication Since 2001
1 Diminnie, J. B.; Liu, X.; Cai, H.; Wu, Z.; Blanton, J. R.; Tuinman, A. A.; Quisenberry, K. T.; Vallet, C. E.; Zuhr, R. A.; Beach, D. B. Peng, Z.-H.; Wu, Y.-D.; Concolino, T. E.; Rheingold, A. L.; Xue, Z. "Reactions of d0 Alkylidene and Amide Complexes with Silanes" Pure Appl. Chem. 2001, 73, 331-335.
2 Ren, Y.; Wu, Y.-D. Tian, A. M. "Recent Research on New and Highly Efficient Catalyst -- Methylrhenium Trioxide", Chinese Journal of Organic Chemistry, 2001, 21, 413-419.
3 Wu, Y.-D., Zhao, Y.-L. " A Theoretical Study on the Origin of Cooperativity in the Formation of 310- and a-Helices ", J. Am. Chem. Soc. 2001, 123, 5313-5319.
4 Wu, Y.-D.; Yu, Z.-X. "Theoretical Study on the Mechanism and Diastereoselectivity of Kulinkuvich Hydroxycyclopropanation", J. Am. Chem. Soc. 2001, 123, 5777-5785.
5 Wu, Y.-D.; Wang, D.-F.; Sessler, J. L. “Conformational Features and Anion-Binding of Calix[4]pyrrole: A Theoretical Study”, J. Org. Chem. 2001, 66, 3739-374
6 Liu, X.; Wu, Z.; Cai, H; Yang, Y.-H.; Vallet, C. E.; Zuhr, R. A.; Beach, D. B.; Peng, Z.-H.; Wu, Y.-D.; Concolino, T. E.; Rheingold, A. L.; Xue, Z. "Reactions of Tetrakis(dimethylamide)-Titanium, -Zirconium and -Hafnium with Silanes. Synthesis of Unusual Amide Hydride Complexes and Mechanistic Studies of Titanium-Silicon-Nitride (Ti-Si-N) Formation" J. Am. Chem. Soc. 2001, 123, 8011-8021.
7 Sheng, Y.-H.; Wu, Y.-D. “Theoretical Study on Alkyne Addition to Molybdenum Alkylidenes: The Preference of a and b Additions”, J. Am. Chem. Soc. 2001, 123, 6662-6668.
8 Yu, Z.-X.; Dang, Q.; Wu, Y.-D. "Aromatic dienophiles. I: A Theoretical Study of Inverse-electron Demand Diels-Alder Reaction between 2-Aminopyrrole and 1,3,5-Triazine", J. Org. Chem. 2001, 66, 6029-6036.
9 Yang, D.; Li, B.; Ng, F.-F.; Yan, Y.-L.; Qu, J.; Wu, Y.-D. "Synthesis and Characterization of Chiral N-O Turns Induced by alpha-Aminoxy Acids", J. Org. Chem. 2001, 66, 7303-7312.
10 Zhao, Y.-L.; Wu, Y.-D. "A Theoretical Study on b-Sheet Models: Is the Formation of Hydrogen Bond Network Cooperative?", J. Am. Chem. Soc. 2002, 124, 1570-1571.
11 Liu, H.-C.; Wang, C.-S.; Guo, W.; Wu, Y.-D.; Yang, S.-H. "Formation and Decomposition of Distonic o-, m-, and p-Benzyne Radical Cations from Photolysis of Mg+(o-, m-, p-C6H4F2)", J. Am. Chem. Soc. 2002, 124, 3794-3798.
12 Jiang, H.; Liu, Y.-C.; Li,† J.; Wang, G.-W.;† Wu, Y.-D.; Wang, Q.-M.; Mak, T. C. W. “The Novel Photoinduced Coupling Reaction of 9-Fluorenylidenemalononitrile with 10-Methyl-9,10-dihydroacridine”, J. Chem. Soc. Chem. Commun. 2002, 882-883.
13 Lin, J.-Q.; Luo, S.-W.; Wu, Y.-D. “Theoretical Study on the b-Sheets Formed by b-peptides”, J. Comput. Chem. 2002, 23, 1551-1558 (invited for a special issue in memory of P. Kollman).
14 Yang, D.; Qu, J.; Li, W.; Ren, Y.; Wang, D.-P.; Wu, Y.-D. “A Cyclic Hexapeptide of D,L-a-Aminoxy Acids as A Selective Receptor for Chloride Ion”, J. Am. Chem. Soc. 2002, 124, 12410-12411.
15 Blanton, J. R.; Chen, T.; Diminnie, J. B.; Cai, H.; Wu. Z.-Z.; Li, L.-T.; Sorasaenee, K. R.; Quisenberry, K. T.; Pan, H. J.; Wang, C.-S.; Choi, S. H.; Wu, Y.-D.; Lin, Z.-Y.; Guzei, I. A.; Rheingold, A. L.; Xue, Z. L. “Silyl-substituted alkylidens: preparation of the novel complexes and mechanistic studies of their formation from reactions of alkylidens with silanes and silyl-to-alkylidyne migrations” J. Mol. Cat. A. Chem. 2002, 190, 101-108.
16 Wu, Y.-D.; Lin, J.-Q.; Zhao, Y.-L. “Theoretical Study of Poly-b-alanine Models: Intrinsic Preferences of Helical Structures” , Helv. Chim. Acta. 2002, 3144-3160. (invited for a special issue in honoring D. Seebach’s 65th birthday).
17 Wu, Y.-D.; Peng, Z.-H. “Theoretical Studies on the Ring-Opening Metathesis Reaction of Norbornadiene with Molybdenum Alkylidenes”, Inorg. Chim. Acta 2003, 345, 241-254. (invited for a special issue in honoring R. R. Schrock’s achievements).
18 Yu, Z.-X.; Wu, Y.-D. “A Theoretical Study of the Mechanisms and Regiochemistry of the Reactions of 5-Alkoxyoxazole with Thioaldehyde, Nitroso Compound and Aldehyde”, J. Org. Chem. 2003, 68, 412-420.
19 Yu, Z.-X.; Wu, Y.-D. “A DFT Study of Regio- and Stereochemistry of the Lewis-Acid-Catalyzed Reactions of 5-Alkoxyoxazoles with Aldehyde: Aryl Substituent at the 2 Position of 5-Alkoxyoxazole is Critical to the Formation of 4-Alkoxycarbonyl-2-Oxazoline”, J. Org. Chem. 2003, 68, 421-432.
20 Li, Y.-X.; Wu, Y.-D. “A Theoretical Study on the Structure of Poly-(R)-3-Hydroxybutanoic Acid”, J. Phys. Chem. A.2003, 107, 5128-5137.
21 Tang, Z.; Fan Jiang, F.; Yu, L.-T. Xui, X.; Gong, L.-Z.; Mi, A.-Q.; Jiang, Y.-Z.; Wu, Y.-D. “Novel Small Organic Catalysts for Highly Enantioselective Direct Aldol Reactions”, J. Am. Chem. Soc. 2003, 125, 5262-5263.
22 Chung, L.-W.; Wu, Y.-D.; Trost, B. M.; Ball, Z. M. “A Theoretical Study on the Regio- and Stereo-selectivities of Hydrosilylation Catalyzed by Cationic Ruthenium Complexes”, J. Am. Chem. Soc. Web-published on August 28, 2003.
23 Yu, Z.-X.; Wu, Y.-D. “A Coarctate Transition State for Alkene Episulfidation by Dinitrogen Sulfide”, J. Org. Chem. 2003, 68, 6049-6052.
24 Wang, G.-W.; Zhang, X.-H.; Zhan, H.; Guo, Q.-X.; Wu, Y.-D. “Accurate Calculation, Prediction and Assignment of 3He NMR Chemical Shifts of Helium-3-Encapsulated Fullerenes and Fullerene Derivatives”, J. Org. Chem. 2003, 68, 6732-6738.
25 Liu, H.-C.; Yang, S.-H.; Zhang, X.-H.; Wu, Y.-D. “Unusual Chemistry of the Complex Mg·+(2-fluoropyridine) Activated by the Photoexcitation of Mg·+” J. Am. Chem. Soc. in press.
26 Yang, D.; Li, W.; Qu, J.; Luo, S.-W.; Wu, Y.-D. “A New Strategy to Induce γ-Turns: Peptides Composed of Alternating a-Aminoxy Acids and a-Amino Acids” J. Am. Chem. Soc. in press
27 Yang, D.; Qu, J.; Wang, D.-P.; Ren, Y.; Wu, Y.-D. “A Novel b-Turn Structure Induced by Two Consecutive D,L-a-Aminoxy Acids”, J. Am. Chem. Soc. Accepted.
28 Zhang, H.-L.; Jiang, F.; Zhang, X.-M.; Cui, X.; Gong, L.-Z.; Mi, A.-Q.; Jiang, Y.-Z.; Wu, Y.-D. “Comprehensive Experimental and Theoretical Studies on the Fine Modification of (1R, 2S)-1,2-Diphenyl-2-aminoethanol for Highly Enantioselective Dialkylzinc Addition to N-Diphenylphosphinoyl Arylimine” Chem. Eur. J. accepted.
[url]http://home.ust.hk/%7Echydwu/[/url]
Prof. YiJing Yan
[attach]4439[/attach]Prof. YiJing Yan
Professor
Department of Chemistry
HKUST
Tel: (852) 2358-7388
Fax: (852) 2358-1594
Send E-mail to me
Research Interests
Theoretical chemical physics. Nonlinear spectroscopies, chemical reactions and molecular dynamics in solutions; Optimal quantum control; Electro-optical processes in molecular assembly; Quantum dissipation and many-particle dynamics; Long-range charge transfer/transport in biological molecules and polymers; Protein-folding kinetics; Quantum computing and information.
Education
Ph.D. (2/89): Chemistry, University of Rochester, Rochester, NY.
Advisor: Professor Shaul Mukamel.
Thesis: "Molecular Nonlinear Optical Line Shapes and Solvaon Dynamics"
B.S. (1/82): Chemistry, Fudan University, Shanghai, China
Professional Experience
Professor, 7/04; Associate Professor (A) 1/01; (B) 1/98; Assistant Professor, 2/94;
Department of Chemistry, Hong Kong University of Science and Technology
Research Associate Professor, 6/92-1/94;
Department of Chemistry and Institute for Nonlinear Science, University of California, San Diego
Postdoctoral Research Associate (with Professor Kent R. Wilson), 5/90-5/92;
Department of Chemistry, University of California, San Diego
Postdoctoral Research Associate (with Professor Shaul Mukamel), 2/88-4/90;
Department of Chemistry, University of Rochester, Rochester, NY
Adjunct/Guest Professorships
University of Science and Technology of China, Hefei, China
Dalian Institute of Chemical Physics, CAS, Dalian, China
Zhongshan University, Guangzhou, China
Nanjing University, Nanjing, China
Fudan University, Shanghai, China
Shangdong University, Jinan, China
Honor/Award:
1999: Outstanding Overseas Young Scientist, NNSF, China
2003: Outstanding Overseas Scientist, CAS, China
Professional/Editorial Services
Editorial/Advisory board:
Chinese Journal of Chemical Physics (2002--)
Journal of Theoretical and Computational Chemistry (2002--)
Referee for Journals:
Chemical Physics Letters, Chemical Physics, Journal of Chemical Physics,
Journal of Physical Chemistry, Physics Letters A, and Computer Physics Communications
Publications
"Trapping and Hopping of Dication Bipolaron in DNA", J. H. Wei, L. X. Wang, K. S. Chan and Y. J. Yan, (2005)
"Transverse Modes of Slow Light Propagation in Eletromagnetically Induced Transparency Media", J. Cheng, Y. J. Yan and S. S. Han, (2005)
"Nonlinear Propagation of Ultraslow Pulses in Eletromagnetically Induced Transparency Mediums", J. Cheng, Y. J. Yan and S. S. Han, (2005)
"Analysis of Resolution and Noise in Ghost Imaging with Classical Thermal Light". J. Cheng, S. S. Han and Y. J. Yan, (2004; Submitted)
"Spontaneous Relaxation of a Charge Qubit under Electrical Measurement", X.Q. Li, P. Cui, Y.J. Yan, Phys. Rev. Lett. (2005; accepted).
"Kinetic Study for Hopping Conduction through DNA Molecules", Y.G. Yang, P.G. Yin, X.Q. Li, and Y.J. Yan, Appl. Phys. Lett. (2004; submitted).
"Response and Correlation Functions with non-Markovian Dissipation: A Reduced Liouville-Space Theory", Y. Mo, R. X. Xu, P. Cui, and Y.J. Yan, J. Chem. Phys. (2004; in press).
"Exact Quantum Master Equation via the Calculus on Path Integrals", R.X. Xu, P. Cui, X.Q. Li, Y. Mo, and Y.J. Yan, J. Chem. Phys. 122, 041103 (2005); (quant-ph/0409007)
"Quantum Mechanics of Dissipative Systems", Y. J. Yan and R.X. Xu, Ann. Rev. Phys. Chem. 56, 187-219 (2005).
"The Lower Bound on the Entanglement of Formation for Multi-mode Gaussian States", L. Wang, S. S. Li and Y. J. Yan, (2004; summitted).
"A Criterion for Local Interconvertibility between All-Tripartite Gaussian States", L. Wang, S. S. Li and Y. J. Yan, J. Phys. A: Math. Gen. 37, 10699-710 (2004)
"Experimental and Theoretical Studies of Protein Folding-Unfolding", Y. J. Shiu, C. Su, Y. L. Yeh, K. K. Liang, M. Hayashi, Y. Mo, Y. J. Yan and S. H. Lin, J. Chin. Chem. Soc. (Taipei) 51, 1161-1173 (2004).
"Optimal Control of Quantum Non-Markovian Dissipation: Reduced Liouville-Space Theory", R. X. Xu, Y. J. Yan, Y. Ohtsuki, Y. Fujimura, H. Rabitz, J. Chem. Phys. 120, 6600-608 (2004).
" Laser-induced Spectral Broadening and Hole-Burning in Rare Earth Doped Crystals and Coherent Optical Spectroscopy for Frequency Up-conversion", J.Y. Zhou, G.Q. Wang, D.C. Dai, L. Luo, K.S. Wong, and Y. J. Yan, Appl. Phys. B: Lasers and Optics, 78, 753-7 (2004).
" Theory of Pump-Probe Propagation in the Third-order and High-order Nonlinear Optical Mediums", J. Cheng, J. Y. Zhou, and Y. J. Yan, J. Opt. Soc. Am. B 21, 364-369 (2004).
"Quantum Measurement of Solid-State Qubit: A Unified Quantum Master Equation Approach", X. Q. Li, W. K. Zhang, P. Cui, J. S. Shao, Z. S. Ma, and Y. J. Yan, Phys. Rev. B 69, 085315 (2004). (Also in cond-mat/0309574).
"Thermodynamics and Kinetics of Protein Folding: A Mean Field Theory", K. K. Liang, M. Hayashi, Y. J. Shiu, Y. Mo, J. S Shao, Y. J. Yan, and S. H. Lin, Phys. Chem. Chem. Phys. 5, 5300-5308 (2003).
"Application of the Generalized Kinetic Ising Model to the Kinetics of Protein", K. K. Liang, M. Hayashi, Y. J. Shiu, Y. Mo, J. S. Shao, Y. J. Yan, and S. H. Lin, J. Chin. Chem. Soc. (Taipei) 50, 335-38 (2003).
"Hyper-Raman and Surface Enhanced Hyper-Raman Spectra of Benzene, Pyridine and Pyrazine", X. Y. Yu, Q. J. Huang, Q. Luo, X. Y. Li, and Y. J. Yan, J. Infrared & Millimeter Waves, 22, 51-55 (2003).
"A Dynamic Mean Field Theory for Dissipative Interacting Many-Electron Systems: Markovian Formalism and its Implementation", S. Yokojima, G. H. Chen, R. X. Xu, and Y. J. Yan, J. Compt. Chem. 24, 2083-92 (2003).
"A Dynamic Mean Field Theory for Dissipative Interacting Many-Electron Systems", S. Yokojima, G. H. Chen, R. X. Xu, and Y. J. Yan, Chem. Phys. Lett. 369, 495-503 (2003).
"Non-Markovian Quantum Dissipation in the Presence of External Fields", R. X. Xu, Y. Mo, P. Cui, S.H. Lin, and Y. J. Yan, in Advanced Topics in Theoretical Chemical Physics: Prog. Theo. Chem. & Phys. 12, pp.7-40, edited by J. Maruani, R. Lefebvre, and E. Brändas (Kluwer, Dordrecht, 2003).
"Effects of finite beam size and crossing angle on space-time-frequency-resolved pump-probe spectroscopy of optically transparent materials", J. Y. Zhou, H.Y. Sang, J. Cheng, J. Lin, Z.R. Qiu, Y.J. Yan and J. Kuhl, Opt. Comm. 228, 187-200 (2003).
"Characterization of Entanglement Transformation via Group Representation Theory", L. X. Cen, X. Q. Li, and Y. J. Yan, J. Phys. A: Math. Gen. 36, 12267-73 (2003).
"Evaluation of Holonomic Quantum Computation: Adiabatic vs. Nonadiabatic", L. X. Cen, X. Q. Li, Y. J. Yan, H. Z. Zheng, and S. J. Wang, Phys. Rev. Lett. 90, 147902 (2003).
Invited Talks (Selected)
"Semiclassical Dynamics in Liouville Space - Application to Electronic Spectroscopy and Electronic Transfer in Condensed Media", ACS regional meeting, Rochester, November 1987
"Optimal Control of Molecular Dynamics in Phase-space", Workshop on "Control of Molecular Systems", Waterloo, Ontario, Canada, May 31 - June 4, 1992
"Light-Matter Time-Frequency Interference in Pump-Probe Spectroscopies", Western Spectroscopy Association Conference”, Pacific Grove, California, January 27-29, 1993
"Density Matrix Formulation and Classical Molecular Dynamics in Quantum Optical Control", 1994 March Meeting of the American Physical Society, Pittsburgh, Pennsylvania, March 21-25, 1994
"A Unified Theory of Quantum Control and Nonlinear Spectroscopies", XIVth International Conference on Raman Spectroscopies, Hong Kong, August 22-26,1994
"Manupulating Matter Wave Dynamics by Light: Theory and Experiments", The 1st Conference for Worldwide Young Chinese Chemists, Beijing, China, August 20-24, 1995
"Optimal Quantum Control and Pump-Probe Spectroscopy: A Liouville-Space Theory", Pacifichem, Honolulu, Hawaii, December 17-22, 1995
"Control and Detection of Molecular Dynamics in Strong Fields", The Bat-Sheva Seminar on Coherent Control, Neva Ilan, Israel, March 4-8, 1996
"Semiclassical Dynamics, Quantum Control and Detection in Condensed Phases", The 56th Okazaki Conference, Japan, September 27-29, 1996
"Theory of Optimal Phase-Unlocked Pump-Dump Control", Bul. Am. Phys. Soc. 40, 1151 (1997) Joint APS/AAPT Meeting and CAM'97, Washington, DC, April 18-21, 1997
"Semiclassical Methods in Optimal Control and Detection of Molecular Dynamics", International Workshop on Optimal Control of Quantum Dynamics: Theory and Experiment, Ringberg Castle, Tegernsee, Germany, July 25-27, 1999
"Optimal coherent control and some related spectroscopies", Gordon Conference on Quantum Control of Atomic and Molecular Motion, New Hampshire, USA, August 1-6, 1999
"Quantum Dissipation in Ultrafast Nonlinear Spectroscopies", UPS’99. XI International Symposium: Ultrafast Phenomena in Spectroscopy, Taipei, Taiwan, October 25-29, 1999
"Optical Control and Spectroscopies of Molecular Dynamics in Condensed Phases", PACIFICHEM, “Laser Control and Manipulations of Molecules”, Honolulu, Hawaii, USA, December 14-19, 2000
"Quantum Dissipation Theory and its Application to Nonlinear Spectroscopies", Asian Second Conference on Ultrafast Phenomena, Kobe, Japan, 24-26 January 2002
"Quantum Open System: From General Theory to Many-Particle Mean-Field Formulation", Workshop on "Quantum Dynamics of Condensed Phase Systems", Rethimno, Crete, Greece, 24-28 June 2002
"Long-Range Electron Transfer/Transport in DNA", IVth Congress of the International Society for Theoretical Chemical Physics (ICTCP-IV), Marly-le-Roi, France, 9-16 July 2002
"Charge Transport in DNA", First International Conference in Theoretical Chemistry and Life Science, BeiJing, 18-20 August 2003
"Partially Coherent Charge Transport in DNA", International Workshop on Advances in Molecular Electronics: From Molecular Materials to Single Molecule Devices, Dresden, Germany, 23-27 February 2004
[url]http://ihome.ust.hk/%7Eyyan/[/url]
Professor Shihe YANG
[attach]4440[/attach]Professor Shihe YANG (PhD, Rice, 1988)
E-mail: "chsyang (at) ust.hk"
Research Interests:
Physical and inorganic chemistry
One of Dr. Yang’s major research areas is the study of structure, dynamics, and photochemistry of isolated clusters. The study is aimed at understanding a wide diversity of phenomena such as catalysis, nucleation, corrosion, solvation, and photography, to name but a few. Modern state-of-the-art laser-based spectroscopic and mass spectroscopic methods are employed. Novel techniques in generating and characterizing new forms of clusters are also pursued.
Synthesis and characterization of zero-, one and two-dimensional nanoscale materials is Dr. Yang's another important research area. These nano-clusters include higher fullerenes, fullerene-metal derivatives (particularly the exotic endohedral metallofullerenes), and metal and semiconductor nano-particles. Main efforts are focused on the development of new methods for the synthesis of nano-structured materials and the characterization of their unique properties with high potential for future applications.
Recent Publications
"Resonance two-photon ionization spectra of van der Waals complexes p, m, o-C6H4F2...NH3 (ND3)", J. Chem. Phys. 111, 134-139 (1999).
"Magnetic behavior of pure endohedral metallofullerene Ho (at) C82 - a comparison with Gd (at) C82", J. Phys. Chem. B 103, 5928-5932 (1999).
"Synthesis and characterization of a water soluble endohedral metallofullerol", Chem. Mater. 11, 1003-1006 (1999).
"Dehydrogenation and physisorption of saturated hydrocarbons (n-butane and isobutane) on Nbx+", J. Chem. Phys. 109, 8935-8939 (1998).
"Preparation of carbon-coated cobalt nanocrystals in a new gas blow arc reactor and their characterization", J. Phys. Chem. B 102, 3420-3424 (1998).
"Relative yields of endohedral lanthanide metallofullerenes by arc synthesis and their correlation with the elution behavior", J. Phys. Chem. B 102, 10196-10200 (1998).
"X-ray studies of self-assembled monolayers on coinage metals. 1. Alignment and photo-oxidation in 1,8-octanedithiol and 1-octanethiol on Au", Langmuir 14, 5147-5153 (1998).
"The third-order nonlinear optical response of the endohedral metallofullerene Dy (at) C82", Chem. Phys. Lett. 289, 167-173 (1998).
"Reactions of alkaline metal cations with methanol clusters", J. Phys. Chem. A 102, 825-840 (1998).
"Resonant two-photon ionization and fluorescence excitation studies of o, m-difluorobenzene...Ar. Spectral shifts and intermolecular vibrations", J. Chem. Phys. 108, 12-19 (1998).
"Intermolecular vibrations of the van der Waals complex p-C6H4FCH3...Ar", Chem. Phys. 218, 325-330 (1997).
"The absolute cross sections of photoabsorption, photodissociation, and photoionization of the group VIB metal hexacarbonyls at 300-1600 ?", J. Chem. Phys. 106, 9474-9482 (1997).
"Dissociative photoionization of Mo(CO)6 in the photon energy range of 8-40 eV", J. Phys. Chem. A 101, 7194-7199 (1997).
"Resonant two-photon ionization spectra of the van der Waals complexes: C6H5X...N2 (X = F, Cl, Br)", J. Chem. Phys. 105, 5305-5312 (1996).
"Generation of fullerenes and metal-carbon clusters in a pulsed arc cluster ion source (PACIS)", J. Chem. Phys. 104, 6577-6581 (1996).
"Efficient DMF extraction of endohedral metallofullerenes for? HPLC purification", Chem. Mater. 8, 2824-2827 (1996).
"Resonant two-photon ionization spectra of the van der Waals complexes: C6H5X...N2 (X = F, Cl, Br)", J. Chem. Phys. 105, 5305-5312 (1996).
"Two-photon ionization studies of binary aromatic van der Waals clusters: benzene...chlorobenzene and (chlorobenzene)2", J. Chem. Phys. 104, 8843-8851 (1996).
"Isolation and characterization of a new dimetallofullerene Ce2 (at) C82", Angew. Chem. Int. Ed. Engl. 35, 2234-2235 (1996).
"Isolation and characterization of Pr (at) C82 and Pr2 (at) C80", J. Am. Chem. Soc. 118, 11254-11257 (1996).
[url]http://www-chem.ust.hk/faculty_ShiheYANG.html[/url]
Dr. Zhihong Guo
[attach]4441[/attach]Dr. Zhihong Guo
Assistant Professor in The Hong Kong University of Science and Technology
Ph. D: 1998, University of Minnesota
MS 1991, Shanghai Institute of Organic Chemistry
BS 1988, University of Science and Technology of China
Personal information:
Office: HKUST Rm. 4536
Lab: HKUST Rm. 7133
E-mail: [email]chguo@ust.hk[/email]
Phone: office: (852)-23587352
lab: (852)-23857380
Fax: (852)-2358-1594
Mailing Address: Dr. Zhihong Guo
The Hong Kong University of Science and Technology
Department of Chemistry
Clear Water Bay, Kowloon
Hong Kong, China
Research Interests:
Bioorganic chemistry and Chemical Biology
One major effort in Dr. Guo's group is to establish combinatorial libraries for drug screening. Two approaches are being pursued to achieve this goal. One is to use the thioesterases in non-ribosomal peptide synthases to synthesize cyclic peptide libraries. The other is to use extracts from Chinese herbal medicines as a universal library. These libraries will be used in development of novel antibiotics to combat drug resistance of infectious microbial pathogens and screening for inhibitors of amyloid formation for Alzhemier's disease treatment.
The second focus in Dr. Guo's research is directed toward understanding the molecular process in Alzheimer's disease pathogenesis and developing novel drug leads for its treatment. Effort is being made to find whether a common biological event exists to simultaneously cause amyloid beta-peptide aggregation and tauopathy. In addition, molecular basis is being sought for the newly discovered correlation between beta-amyloidosis and tauopathy. Furthermore, using the established combinatorial libraries, leads are being developed against the formation of the two essential lesions in the disease, amyloidosis and neurofibrillary tangles. These projects are designed to contribute positively to establishing a unified pathogenesis for the disease and its treatment and prevention.
Publications:
1. Guo, Zhihong "Phage Display: A Powerful Tool in Biomedical Research" in Frontiers of Biotechnology & Pharmaceuticals, Vol. 2, Huang, Z.; Guo, M.; Reiner, J.; Zhao, K. Eds.; pp32-58 (in press)
2. Chen, Huawei; Zhao, Zongbao; Hallis, Tina M.; Guo, Zhihong; Liu, Hung-wen "Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase" Angew. Chem., Int. Ed. 2001, 40, 607-610
3. Guo, Zhihong; Zhou, Demin; Schultz, Peter G. "Designing Small Molecule Switches for Protein-Protein Interactions" Science 2000, 288, 2042-2045
4. Chen, Huawei; Agnihotri, Gautam; Guo, Zhihong; Que, Nanette L. S.; Chen, Xuemei H.; Liu, Hung-wen "Biosynthesis of Mycarose: Isolation and characterization of enzymes involved in the C-2 deoxygenation" J. Am. Chem. Soc. 1999, 121, 8124-8125
5. Chen, Huawei; Guo, Zhihong; Liu, Hung-wen "Biosynthesis of yersiniose: Attachment of the two-carbon branched-chain is catalyzed by a thiamine pyrophosphate-dependent flavoprotein" J. Am. Chem. Soc. 1998, 120, 11796-11797
6. Chen, Huawei; Guo, Zhihong; Liu, Hung-wen "Expression, purification, and characterization of TylM1, an N, N-dimethyltransferase involved in the biosynthesis of mycaminose" J. Am. Chem. Soc. 1998, 120, 9951-9952
7. Li, Ding; Guo, Zhihong; Liu, Hung-wen "Mechanistic Studies of the Inactivation of Crotonase by (Methylenecyclopropyl) formyl-CoA" J. Am. Chem. Soc. 1996, 118, 275-276
8. Pieper, Patricia A.; Guo, Zhihong; Liu, Hung-wen "Mechanistic Studies of the Biosynthesis of 3,6-Dideoxy Sugars: Stereochemical Analysis of C-3 Deoxygenation" J. Am. Chem. Soc. 1995, 117, 5158-5159
9. Wen, J.; Tian, M., Guo, Z., Chen, Q. "Synthesis and phase-transition of 4-alkoxycarbonylphenyl-4'-n-alkoxy-2,3,5,6-tetrafluorobiphenyl-4-carboxylates" Molecular Crystals and Liquid Crystals Science and Technology Section A- Molecular Crystals and Liquid Crystals 1996, 275, 27-36
10. Wen, Jianxun; Tian, Minquan; Yu, Hongbin; Guo, Zhihong; Chen, Qi "Novel Fluorinated Liquid Crystals. Part 9. Synthesis and Memomorphic Properties of 4-(Alkoxycarbonyl)phenyl 4-[(4-alkoxy-2,3,5,6-tetrafluorophenyl)ethynyl ]benzoates" J. Mater. Chem. 1994, 4, 327-330
Patent:
1. Wen, Jianxun; Chen, Qi; Guo, Zhihong; et al. "Perfluorobenzene Ring-containing Liquid Crystal Compounds" Patent No. CN 1066458 A 921125
Group Members:
Current Group Members:
1. Dr. Xianzhang Bu (卜憲章), Postdoctoral Research Associate, [email]chxzbu@ust.hk[/email]
2. Dr. Guiyang Xie (謝桂陽), Postdoctoral Research Associate, [email]chxie@ust.hk[/email]
3. Mr. Wei Jianwen(衛劍文), Visiting scholar, [email]chwjw@ust.hk[/email]
4. Mr. Wu Xiaoming (吳曉明), Ph. D. graduate student, [email]chwuxm@ust.hk[/email]
5. Mr. Ka Man (William) Wong (王家文), M. Phil. graduate student, [email]chwkmaa@ust.hk[/email]
6. Miss. Ng Na Lee(吳娜莉), undergraduate student, [email]ch_nnl@stu.ust.hk[/email]
7. Miss Lin Sam Sam(林新新), undergraduate student, [email]ch_lss@stu.ust.hk[/email]
8. Mr. Cheung Sin Hang(張善衡),undergraduate student, [email]ch_csh@stu.ust.hk[/email]
9. Mr. Law Chi Wang(羅智鴻),undergraduate student, [email]ch_lcw@stu.ust.hk[/email]
Group Alumni:
1. Mr. Weili Yan (晏為力), Ph. D. graduate student
2. Miss Lo Ming Lai ( 黎露明), undergraduate student
3. Mr. Cheung Kwok Wa (Sam), undergraduate student
4. Miss. Peng Tuohua (彭拓華), Research Assistant
[url]http://ihome.ust.hk/~chguo/[/url]
Dr Wa Hung LEUNG
[attach]4442[/attach]Associate Professor Wa-Hung LEUNG (PhD, Hong Kong, 1989)
E-mail: "chleung (at) ust.hk"
Research Interests:
Inorganic and Organometallic Chemistry
The research interests of Dr Leung are in the field of synthetic inorganic and organometallic chemistry.
(a) Metal complexes with chalcogen donor ligands
Metal-sulfur systems are of signficance due to their central roles in biological and heterogeneous catalysis.Of particular interest are the Ru/S systems which are known to exhibit good catalytic activity toward hydrodesulfurization processes. To model the active sites of metal-sulfide catalysts, ruthenium and osmium complexes with thiolate and dithiolate ligands such as [N(PR2Q)2]- were synthesized.Catalytic activities of these metal-sulfur complexes are investigated.
(b) Heterobimetallic nitrido and dinitrogen complexes
In an effort to elucidate the mechanism of nitrogen fixation, bimetallic dinitrogen and nitrido complexes are synthesized. The bonding and structures and reactivity of these dinitrogen and nitrido bridged complexes are investigated.
(c) Functionalization of sigma-aryl ligands
The aryl ligands osmium tetraaryls, e.g. [Os(C8H9)4] (C8H9 = 2,5-dimethylphenyl), have been succesfully functionalized by bromination, acylation and formylation to give the corresponding homoleptic functionalized aryl complexes. Suzuki coupling of the bromoaryl complex with arylboronic acids afforded a series of homoletpic biaryls complexes of Os(IV). These functionalized aryl complexes will be used as builiding blocks for multimetallics and organometallic oligomers.
(d) Metal complexes with oxygen tripod ligands
Metal complexes with oxygen tripod ligands such as [CpCo{P(O)(OR)2}3]- are synthesized as models for metal aqua ions and the active sites of metal-oxide catalysts The organometallic chemistry and catalytic activity of these complexes will be investigated.
Representative Publications
(1) "Bridged dinitrogen complexes of iron and chromium porphyrins", Inorg. Chem., 2001, 40, 2470-1.
(2) "Ruthenium pentamethylcyclopentadienyl complexes with sulfur and selenium ligands", Organometallics, 2001, 20, 3777-3781.
(3) "Direct functionalization of sigma-aryl ligands. Preparation of homoleptic functionalized aryls of osmium(IV)", Chem. Comm., 2001, 1478-9.
(4) "Synthesis and reactivity of rhenium and osmium complexes with an oxygen tripod ligand", J. Chem. Soc., Dalton Trans., 2000, 51-56.
(5) "Ruthenium benzylidene and vinylidene complexes in a sulfur rich coordination environment", Organometallics, 2000, 19, 2084.
(6) "Ruthenium complexes with [N(PSR2)2]- (R = Ph or Pr)", J. Chem. Soc. Dalton Trans., 2000, 423-430.
(7) "Regioselective ring opening of 1,2-disubstituted epoxides mediated by imido(halo)metal complexes", Synlett, 2000, 677.
(8) "Ruthenium benzylidene and vinylidene complexes in a sulfur rich coordination environment", Organometallics, 2000, 19, 2084.
(9) "Nitrido- and dioxo-osmium complexes with imidodiphosphinochalcogenido ligands", J. Chem. Soc., Dalton Trans., 2000, 3027-3033.
(10) "Ruthenium(II) ammine and hydrazine complexes with [N(QPPh2)2]- (Q = S or Se)", Inorg. Chem., 2000, 39, 5255-5264.
(11) "Synthesis and Electrochemistry of Ruthenium Complexes of an Oxygen Tripod Ligand," Inorg. Chem., 1999, 38, 136-143.
(12) "Reaction of nitridorhenium(V) and osmium(VI) complexes with acylating agents" Inorg. Chem., 1999, 39, 3000-3005.
[url]http://www-chem.ust.hk/faculty_Wa-HungLEUNG.html[/url]
Dr Ian WILLIAMS
[attach]4443[/attach]Associate Professor Ian D. WILLIAMS (PhD, Bristol, 1986)
E-mail: "chwill (at) ust.hk"
Research Interests:
Materials and solid state chemistry
Crystal Engineering
Dr Williams' research aims to modify the properties of crystalline solids through controlled design of their internal structure or architecture. Three main areas are being pursued, organic crystals, metallo-organic framework crystals and inorganic framework crystals.
Representative Publications
"Organo-template Control of Inorganic Structures: A Low Symmetry 2-D Sheet Aluminophosphate" Chem. Commun., 1781-2 (1996).
"Synthesis and Structural Characterisation of 2-D and 3-D Fluorinated Indium Phosphates" Chem. Commun., 781-2 (1997).
"A New Chain Architecture for a 1-D Aluminophosphate, [NH3CH2CH2NH3][AlP2O8H]" Chem. Commun., 1273 -4(1997).
"Non-aqueous Synthesis and Characterisation of a New 2-D Layered Aluminophosphate" J. Solid State Chem., 129, 37-44 (1997)
"A Metal Rich Fluorinated Indium Phosphate with 14 Membered Ring Cavities" Chem. Mater., 10, 773 (1998).
"Zirconium Phosphates of Variable Dimension Templated by Ethylene Diamine" J. Solid State Chem., 140, 46-55 (1998)
"Two New Aluminophosphate Frameworks Templated by Imidazolium Ions; 2[N2C3H5][AlP2O8H.2H2O] and 2[N2C3H5][Al3P4O16H]" J. Solid State Chem., 136, 141-146 (1998).
"An Organically Templated Vanadoborate Polymer 2[enH2]4[enH] [V6B22O53H8]5H2O" Chem. Commun., 2463 (1998)
"A Chemically Functionalizable Nanoporous Material, [Cu3(TMA)2(H2O)3]n" Science, 283, 1148 (1999).
"A 2-D Mixed-Metal Phosphate Templated by Ethylene Diamine, [enH2][CoIn(PO4)2H(OH2)2F2]." J. Solid State Chem., 142, 241-246 (1999).
"Organo-directed Synthesis of a 3-D Open-Framework Mixed-Metal Oxide, [enH2][Mn3V4O14(H2O)2], incorporating Metal Trimer Building Blocks" Solid State Sciences, 1, 000 (2000).
"Synthesis and Properties of Vanadoborate Cluster Materials" Contemporary Boron Chemistry, ed. Wade, Marder and Davidson, R.S.C. Publications, (2000).
[url]http://www-chem.ust.hk/faculty_IanDWILLIAMS.html[/url]
Dr Bing XU
[attach]4444[/attach]Associate Professor
Ph.D., University of Pennsylvania
Our research focuses on the interdisciplinary frontier of materials chemistry. We integrate the knowledge and techniques in organic chemistry, materials science, surface chemistry, biochemistry, and nanotechnology to design new biofunctional materials, including nanomaterials, for the exploration in biomediceine (e.g., molecular drug delivery, cancer therapy, biomedical diagnostics, and biomimetics), and other fundamental problems in nanoscience and biological science.
The Research Group of Bing Xu
2002-present
78 Liang, G. L.; Xu, K. M.; Li, L. H.; Wang, L.; Kuang, Y.; Yang, Z. M.; Xu, B.* "Using Congo red to report intracellular hydrogelation resulted from self-assembly of small molecules" Chem. Commun. 2007, 4096-4098.
77 Gao, J. H.; Zhang, B.; Gao, Y.; Pan, Y.; Zhang, X. X.; Xu, B.* "Fluorescent Magnetic Nanocrystals by Sequential Addition of Reagents in a One-Pot Reaction: A Simple Preparation for Multifunctional Nanostructures" J. Am. Chem. Soc. 2007, 129, 11928-11935
76 Yang, Z. M.; Xu, K. M.; Guo, Z. F.; Guo, Z. H.; Xu, B.* "Intracellular Enzymatic Formation of Nanofibers Results in Hydrogelation and Regulated Cell Death" Adv. Mater. 2007, 17, 3152-3156.
75 Yang, Z. M.; Liang, G. L.; Guo, Z. F.; Guo, Z. H.; Xu, B.* "Intracellular Hydrogelation of Small Molecules Inhibits Bacterial Growth" Angew. Chem. Int. Ed., 2007, 46, 8216-8219.
74 Yang, Z. M.; Gu, H. W.; Du, J.; Gao, J. H.; Zhang, B.; Zhang, X. X.; Xu, B.* "Self-assembled hybrid nanofibers confer a magnetorheological supramolecular hydrogel", Tetrahedron, 2007, 63, 7349-7357.
73 Wang, Q.G.; Yang, Z. M.; Zhang, X. Q.; Xiao, X. D.; Chang, C. K.*; Xu, B.* "A Supramolecular Hydrogel-Encapsulated Hemin as an Artificial Enzyme to Mimic Peroxidase" Angew. Chem. Int. Ed., 2007, 46, 4285-4289
72 Yang, Z. M.; Xu, B.* "Supramolecular hydrogels based on biofunctional nanofibers of self-assembled small molecules" J. Mater. Chem., 2007, 17, 2385-2393.
71 Yang, Z. M.; Liang, G. L.; Xu, B.* "Enzymatic Control of the Self-Assembly of Small Molecules: A New Way to Generate Supramolecular Hydrogels" Soft Matter, 2007, 2, 515-520.
70 Yang, Z. M.; Liang, G. L.; Ma, M. L.; Gao, Y; Xu, B.* "In Vitro and In Vivo Enzymatic Formations of Supramolecular Hydrogels Based on Self-Assembled Nanofibers of a beta-Amino Acid Derivative" Small, 2007, 3, 558-562.
69 Wang, Q. G.; Yang, Z. M.; Wang, L.; Ma, M. L.; Xu, B.* "Molecular Hydrogel-Immobilized Enzymes Exhibit Superactivity and High Stability in Organic Solvents" Chem. Comm. 2007, 1032-1034.
68 Yang, Z. M.; Xu, B* "Conjugates of naphthalene and dipeptides confer molecular hydrogelators with high efficiency of hydrogelation and superhelical nanofibers" J. Mater. Chem., 2007, 17, 850-854
67 Yang,Z. M.; Liang, G. L.; Ma, M. L.; Abbah, A. S.; Lu, W. W.; Xu, B.* "D-glucosamine-based supramolecular hydrogels to improve wound healing" Chem. Commun., 2007, 843-845.
66 Gao, J. H.; Liang, G. L.; Zhang, B.; Kuang, Y.; Zhang, X. X.; Xu, B.* "FePt@CoS2 Yolk-shell Nanocrystals as A Potent Agent to Kill HeLa Cells" J. Am. Chem. Soc. 2007, 129, 1428-1433.
65 Yang, Z. M.; Ho, P.-L.; Liang, G. L.; Chow, K. H.; Wang, Q. G.; Cao, Y.; Guo, Z. H.; Xu, B* "Using beta-Lactamase to Trigger Supramolecular Hydrogelation" J. Am. Chem. Soc. 2007, 129, 266-267.
64 Gao, J. H.; Li, L. H.; Ho, P. L.; Mak, G. C.; Gu, H. W.; Xu, B.* "Combining Fluorescent Probes and Biofunctional Magnetic Nanoparticles for Rapid Detection of Bacteria in Human Blood" Adv. Mater. 2006, 18, 3145-3148
63 Liang, G. L.; Wang, L.; Yang, Z. M.; Koon, H.; Mak, N. K.; Chang, C. K.*; Xu, B.* "Using enzymatic reaction to enhance photodynamic therapy effect of porphyrin dityrosine phosphates" Chem. Commun. 2006, 5021-5023.
62 Yang, Z. M.; Xu, B* "Using Enzyme to Command Molecular Hydrogelation" Adv. Mater. 2006, 18, 3043-3047.
61 Wang, L.; Yang, Z. M.; Gao, J. H.; Xu, K. M.; Gu, H. W.; Zhang, B.; Zhang, X. X.; Xu, B.* "A Biocompatible Method of Decorporation: Bisphosphonate Modified Magnetite Nanoparticles to Remove Uranyl Ions from Blood" J. Am. Chem. Soc. 2006, 128, 13358-13359.
60 Nia, G.X.; Lu, W.W.*; Xu, B.; Chiua, K. Y.; Yang, C.; Li, Z.Y.; Lam ,W.M.; Luk, K.D.K. "Interfacial behaviour of strontium-containing hydroxyapatite Cement" Biomaterials 2006, 27, 5127-5133.
59 Wang, L; Zhang, M.; Xu, B* "The first pamidronate containing polymer and copolymer" Chem. Commun. 2006, 2795-2797.
58 Yang, Z. M.; Liang, G. L.; Wang, L. Xu, B.* "Using a Kinase/Phosphatase Switch to Regulate a Supramolecular Hydrogel and Forming the Supramolecular Hydrogel in vivo" J. Am. Chem. Soc. 2006, 128, 3038-3043.
57 Gu, H. W.; Xu, K. M.; Xu, C. J.; Xu, B.* "Biofunctional Magnetic Nanoparticles for Protein Separation and Pathogen Detection" (feature article) Chem. Commun. 2006, 941-949.
56 Yang, Z. M.; Liang, G. L.; Xu, B.* "Supramolecular Hydrogels Based on beta-Amino Acid Derivatives" Chem. Commun. 2006, 738-740.
55 Gao, J. H.; Zhang, B.; Zhang, X. X.; Xu, B.* "Magnetic Dipolar Interaction Induced Self-Assembly Affords Wires of Cobalt Selenide Hollow Nanocrystals" Angew. Chem. Int. Ed. 2006, 45, 1220-1223.
54 Yang, Z. M.; Xu, K. M.; Wang, L.; Gu, H. W.; Wei, H.; Zhang, M. J.; Xu, B.* "Self-Assembly of Small Molecules Affords Multifunctional Supramolecular Hydrogels for Topically Treating Simulated Uranium Wounds" Chem. Commun. 2005, 4414-4416.
53 Zheng, R. K.; Gu, H. W.; Xu, B.; Zhang, X. X.* "Memory effects in a nanoparticles system: the low field magnetization and ac susceptibility measurements" Phys. Rev. B, 2005, 72, 14416.
52 Gu, H. W.; Xu, K. M., Yang, Z. M., Chang, C. K.; Xu, B.* "Synthesis and Cellular Up-take of Porphyrin Decorated Iron Oxide Nanoparticles-A Potential Candidate for Bimodal Anticancer Therapy" Chem. Commun. 2005, 4270-4272.
51 Li, L. H.; Xu, B.* "Multivalent Vancomycins and Related Antibiotics Against Infectious Diseases" Current Pharm. Design, 2005, 11, 3111-3124.
50 Gu, H. W.; Zheng, R. K.; Liu, H.; Zhang, X. X.; Xu, B.* "Direct Synthesis of a Bimodal Nanosponge Based on FePt and ZnS" Small, 2005, 1, 402-406.
49 Gu, H. W.; Yang, Z. M.; Gao, J. H.; Chang, C. K.; Xu, B.* "Heterodimers of Nanoparticles: Formation at a Liquid-Liquid Interface and Particle-Specific Surface Modification by Functional Molecules" J. Am. Chem. Soc. 2005, 127, 34-35.
48 Zhang, Y.; Yang, Z. M.; Yuan, F.; Gu, H. W.; Gao, P.; Xu, B.* "Molecular Recognition Remolds the Self-Assembly of Hydrogelators and Increases the Elasticity of the Hydrogel by 10^6-Fold" J. Am. Chem. Soc. 2004, 126, 15028-15029.
47 Yang, Z. M.; Xu, B.* "A Simple Visual Assay Based on Small Molecule Hydrogels for Detecting Inhibitors of Enzymes" Chem. Commun. 2004, 2424-2425.
46 Yang, Z. M., Gu, H. W., Fu, D. G., Gao, P., Lam, K. J. K., Xu, B.* "Enzymatic Formation of Supramolecular Hydrogels" Adv. Mater. 2004, 16, 1440-1444.
45 Gu, H. W.; Zheng, R. K.; Zhang, X. X.; Xu, B.* 'Using Soft Lithography to Pattern Highly Oriented Polyacetylene (HOPA) Films via Solventless Polymerization" Adv. Mater. 2004, 16, 1356-1359.
44 Xu, C. J.; Xu, K. M.; Gu, H. W.; Zheng, R. K.; Liu, H.; Zhang X. X.; Guo, Z. H.; Xu, B.*"Dopamine as A Robust Anchor to Immobilize Functional Molecules on the Iron Oxide Shell of Magnetic Nanoparticles" J. Am. Chem. Soc., 2004, 126, 9938-9939.
43 Gu, H. W.; Fu, D. G.; Weng, L.-T.; Xie, J.; Xu, B.* “Solventless Polymerization to Grow Thin Films on Solid Substrates” Adv. Func. Mater. 2004, 14, 492-500.
42 Gu, H. W., Zheng, R. K., Zhang, X. X., Xu, B.* “Facile One-Pot Synthesis of Bifunctional Heterodimers of Nanoparticles: A Conjugate of Quantum Dot and Magnetic Nanoparticles” J. Am. Chem. Soc. 2004, 126, 5664-5665.
41 Xu, C. J.; Xu, K. M.; Gu, H. W.; Zhong, X. F.; Guo, Z. H.; Zheng, R. K.; Zhang, X. X.; Xu, B.* “Nitrilotriacetic Acid Modified Magnetic Nanoparticles as a General Agent to Bind Histidine-Tagged Proteins” J. Am. Chem. Soc. 2004, 126, 3392-3393.
40 Yang, Z. M.; Gu, H. W.; Zhang, Y.; Wang, L.; Xu, B.* “Small Molecule Hydrogels Based on a Class of Antiinflammatory Agents” Chem. Commun, 2004, 208-209.
39 Gu, H. W.; Ho, P. L.; Tsang, K. W. T.; Wang, L.; Xu, B.* “Using Biofunctional Magnetic Nanoparticles to Capture Vancomycin Resistant Enterococci and Other Gram-Positive Bacteria at Ultralow Concentration” J. Am. Chem. Soc. 2003, 125, 15702-15703.
38 Zhang, Y.; Gu, H. W.; Yang, Z. M.; Xu, B.* “Supramolecular Hydrogels Respond to Ligand-Receptor Interaction” J. Am. Chem. Soc. 2003, 125, 13680-13681.
37 Gu, H. W.; Xu, C. J.; Weng, L.-T.; Xu, B.* “Solventless Polymerization: Spatial Migration of a Catalyst to Form Polymeric Thin Films in Microchannels” J. Am. Chem. Soc. 2003, 125, 9256-9257.
36 Xing, B. G.; Yu, C.-W.; Ho, P. L.; Chow, K.; Cheung, T.; Gu, H. W.; Cai, Z. W.; Xu, B.* “Multivalent Antibiotics via Metal Complexes: Potent Divalent Vancomycins Against Vancomycin Resistant Enterococci (VRE)” J. Med. Chem. 2003, 46, 4904-4909.
35 Gu, H. W.; Ho, P. L.; Tong, E.; Wang, L.; Xu, B.* “Presenting Vancomycin on Nanoparticles to Enhance Antimicrobial Activities” Nano. Lett. 2003, 3, 1261-1263.
34 Xing, B. G.; Ho, P. L.; Yu, C.-W.; Chow, K.-H.; Gu, H. W.; Xu, B.* “Self-Assembled Multivalent Vancomycin on Cell Surfaces Against Vancomycin-Resistant Enterococci (VRE)” Chem. Commun. 2003, 2224-2225.
33 Gu, H. W.; Fu, D. G.; Xu, C. J.; Tang, J.; Xie, J. and Xu, B.* “Solventless Polymerization at the Gas/Solid Interface to Form Polymeric Thin Films and Its Applications” Materials Research Society Symposium Proceedings (2003), 776 (Unconventional Approaches to Nanostructures with Applications in Electronics, Photonics, Information Storage and Sensing), 177-185.
32 Gu, H. W., Ho, P. L.; Tsang, K. W. T.; Yu, C. W.; Xu, B.* “Using Biofunctional Magnetic Nanoparticles to Capture Gram-negative Bacteria at a Ultra-Low Concentration” Chem. Commun. 2003, 1966-1967.
31 Gu, H. W.; Xu, B.*; Rao, J. C.; Zheng, R. K.; Zhang, X. X.; Fung, K. K., Wong, C. Y. C. “Chemical Synthesis of Narrowly Dispersed SmCo5 Nanoparticles” J. Appl. Phys. 2003, 93, 7589-7591.
30 Xing, B. G.; Yu, C.-W.; Chow, K.; Fu, D. G.; Ho, P. L.; Xu, B.* “Hydrophobic Interaction and Hydrogen Bonding Cooperatively Confer A Vancomycin Hydrogel: A Potential Candidate for Biomaterials” J. Am. Chem. Soc., 2002, 124, 14846-14847.
29 Xing, B. G.; Choi, M.-F.; Xu, B.* “Spontaneous Enrichment of Organic Molecules from Aqueous and Gas Phases Into A Stable Metallogel” Langmuir, 2002, 18, 9654-9658.
28 Xing, B. G.; Choi, M.-F.; Xu, B.* “Design of Coordination Polymer Gels as Stable Catalytic Systems” Chem. Eur. J. 2002, 8, 5028-5032.
27 Fu, D. G.; Weng, L.-T.; Du, B. Y.; Tsui, O. K. C.; Xu, B.* “Solventless Polymerization at the Gas/Solid Interface to Form Polymeric Thin Films” Adv. Mater. 2002, 14, 339-343.
26 Xing, B. G.; Choi, M.-F.; Xu, B.* “A Stable Metal Coordination Polymer Gel Based on A Calix[4]arene and Its ‘Uptake’ of Nonionic Organic Molecules from the Aqueous Phase” Chem. Commun., 2002, 362.
Works before joining HKUST
25 Yu, H.; Xu, B.; Swager, T. M.* “A Proton-Doped Calix[4]Arene-Based Conducting Polymer” J. Am. Chem. Soc. 2003, 125, 1142-1143.
24 Arias, F.; Oliver, S. R. J.; Xu, B.; Holmlin, R. E.; Whitesides, G. M. “Fabrication of Metallic Heat Exchangers Using Sacrificial Polymer Mandrils”, J. MEMS. 2001, 10, 107.
23 Arias, F.; Xu, B.; Schuller, O.; Kenis, P.; Deng, T.; Whitesides, G. M. “Fabrication and Characterization of Microscale Sandwich Beams" J. Mater. Res. 2001, 16, 597.
22 Choi, I. S.; Weck, M.; Xu, B.; Jeon, N. L.; Whitesides, G. M. “Mesoscopic, Templated Self-Assembly at the Fluid-Fluid Interface”, Langmuir, 2000, 16: 2997.
21 Deng, T.; Tien, J.; Xu, B.; Whitesides, G. M. “Using Patterns in Microfiche as Photomasks in 10 mm Scale Microfabrication”, Langmuir, 1999, 15, 6575
20 Qin, D.; Xia, Y.; Xu, B.; Yang, H.; Zhu, C.; Whitesides, G. M. “Fabrication of Ordered Two-Dimensional Arrays of Micro- and Nanoparticles Using Patterned Self-Assembled Monolayers as Templates” Adv. Mater. 1999, 11, 1433.
19 Xu, B.; Arias, F.; Brittian, S. T.; Zhao, X.-M.; Grzybowski, B.; Torquato, S.; Whitesides, G. M. “Making Negative Poisson's Ratio Microstructures by Soft Lithography” Adv. Mater. 1999, 11, 1186.
18 Jeon, N. L.; Choi, I. S.; Xu, B.; Whitesides, G. M. “Large-Area Patterning by Vacuum-Assisted Micromolding”, Adv. Mater. 1999, 11, 946.
17 Rao, J.; Yan, L.; Xu, B.; Whitesides, G. M. “Using Surface Plasmon Resonance to Study the Binding of Vancomycin and Its Dimer to Self-Assembled Monolayers Presenting D-Ala-D-Ala” J. Am. Chem. Soc. 1999, 121, 2629.
16 Xu, B.; Arias, F.; Whitesides, G. M. “Making Honeycomb Microcomposites by Soft Lithography” Adv. Mater. 1999, 11, 492.
15 Xu, B.; Miao, Y.; Swager, T. M. “Palladium Couplings on a Metallocalix[4]arene: A Efficient Synthesis of New Functionalized Cavities” J. Org. Chem. 1998, 63, 8561.
14 Fu, D.-K.; Xu, B.; Swager, T. M. “Alternating Poly(Pyridylvinylenephenylenevinylene): Synthesis and Solid State Organizations” Tetrahedron, 1997, 53, 15487.
13 Harvey, P. D.; Gagnon, J.; Provencher, R.; Xu, B.; Swager, T. M. “Tungsten and Molybdenum Oxo Complexes of Tetrakis(Phenyldiazenyl)Calix[4]Arene Substituted Derivatives: EHMO Calculations, Spectroscopic Characterization, and Perturbations of the Photophysical Properties by Neutral Guest Molecules” Can. J. Chem.1996, 74, 2279
12 Xu, B.; Carroll, P. J.; Swager, T. M. “Chiral Metallocalix[4]arene: Resolution via Diastereomer Tungsten Alkoxide” Angew. Chem. Intl. Ed. Engl. 1996, 35, 2094.
More:[url]http://ihome.ust.hk/%7Echbingxu/Pub.htm[/url]
[url]http://ihome.ust.hk/%7Echbingxu/[/url]
Dr Jian Zhen YU
[attach]4445[/attach]Jian Zhen Yu
Associate Professor
Department of Chemistry
Hong Kong University of Science & Technology
Clear Water Bay, Kowloon, Hong Kong
Tel: 852-2358-7389, Fax: 852-2358-1594
Email: [email]chjianyu@ust.hk[/email]
BS: Nanjing University, 1989
MS: University of Montana, Missoula, 1992
PhD: University of North Carolina-Chapel Hill, 1996
Post-doc.:University of North Carolina-Chapel Hill, 1996-97
Post-doc.: California Institute of Technology, 1997-99
Research Area: Environmental Analytical Chemistry, Atmospheric Chemistry
Chemical characterization of water-soluble organic aerosols, sources and formation mechanisms
1.
X.-F. Huang, J. Z. Yu, Is Vehicular Exhaust a Significant Primary Source of Oxalic Acid in Ambient Aerosols? Geophys. Res. Lett. 34, 2007, L02808, doi: 10.1029/2006GL028457.
2.
X.-F. Huang, J. Z. Yu, L.-Y. He, Z. B. Yuan, Water-soluble Organic Carbon and Oxalate in Aerosols at a Coastal Urban Site in China: Size Distribution Characteristics, Sources and Formation Mechanisms, J. Geophys. Res. ¨CAtmosphere, 111, 2006, D22212, doi:10.1029/2006JD007408.
3.
J. Z. Yu, X.-F. Huang, J. Xu, M. Hu, When sulfate goes up, so does oxalate: Implication for the formation mechanisms of oxalate. Environ. Sci. Technol. 2005, 39 (1), 128-133.
4.
H. Yang, J. H. Xu, W-S. Wu, C. H. Wan, J. Z. Yu, Chemical characterization of water-soluble organic aerosols at Jeju Island collected during ACE-Asia, Environ. Chem. 2004, 1 (1), 13-17, doi:10.1071/EN04006. reprint
5.
B. T. Mader, J. Z. Yu, J. H. Xu, Q. F. Li, W. S. Wu, R. C. Flagan, and J. H. Seinfeld, Molecular Composition of the Water Soluble Fraction of Atmospheric carbonaceous Aerosols Collected during ACE-Asia, J. Geophys. Res. 2004, 109, D06206, doi:10.1029/2003JD004105.
6.
J. Z. Yu, H. Yang, H. Y. Zhang, A. K. H. Lau, Size Distributions of Water-Soluble Organic Carbon in Ambient Aerosols and its Size-resolved Thermal Characteristics, Atmos. Environ. 2004, 38 (7), 1061-1071.
7.
H. Yang, Q. F. Li, and J. Z. Yu, Comparison of Two Methods for the Determination of Water-Soluble Organic Carbon in Atmospheric Particles, Atmos. Environ., 2003, 37 (6),865-870.
Measurements of EC and OC using thermal methods: method characterization and applications
8.
X.-F. Huang, J. Z. Yu, L.-Y. He, M. Hu, Size Distribution Characteristics of Elemental Carbon Emitted from Chinese Vehicles: Results of a Tunnel Study and Atmospheric Implications, Environ. Sci. Technol. in press, 2006.
9.
J. C. Chow, J. G. Watson, L.-W. A. Chen, G. Paredes-Miranda, M.-C. O. Chang, D. Trimble, K. Fung, H. Zhang, J. Z. Yu, Refining Temperature Measures in Thermal/Optical Carbon Analysis, Atmos. Chem. Phys. 5, 2005, 2961-2972.
10.
B.T. Mader, J.J. Schauer, J.H. Seinfeld, R.C. Flagan, J.Z.Yu, H. Yang, Ho-JinLim, B.J. Turpin, J. T. Deminter, G. Heidemann, M. S. Bae, P. Quinn, T. Bates, D.J. Eatough, B.J. Huebert, T., Bertram, and S. Howell, Sampling Methods Used for the Collection of Particle-Phase Organic and Elemental Carbon During ACE-Asia, Atmos. Environ., 2003, 37 (11), 1435-1449.
11.
J.J. Schauer, B.T. Mader, J. T. DeMinter, G. Heidemann, M. S. Bae, J.H. Seinfeld, R.C. Flagan, R.A. Cary, D. Smith, B.J. Huebert, T. Bertram, S. Howell, J. T. Kline, P. Quinn, T. Bates, B. Turpin, H. J. Lim, J. Z. Yu, H. Yang, and M. D. Keywood, Ace-Asia Intercomparison of a Thermal-Optical Method for the Determination of Particle-Phase Organic and Elemental Carbon, Environ. Sci. Technol., 2003, 37 (5), 993-1001.
12.
P. Y. Chuang, R. M. Duvall, M. S. Bae, A. Jefferson, J. J. Schauer, H. Yang, J. Z. Yu, J. Kim, Observation of Elemental Carbon and Absorption During Ace-Asia and Implications for Aerosol Radiative Properties and Climate Forcing, J. Geophys. Res., 2003, 108 (D23), 8634, doi:10.1029/2002JD003254.
13.
H. Yang and J. Z. Yu, Uncertainties in Charring Correction in the Analysis of Elemental and Organic Carbon in Atmospheric Particles by Thermal/Optical Methods, Envron. Sci. Technol., 2002, 36 (23), 5199-5204.
14.
J. Z. Yu, J. H. Xu, and H. Yang, Charring Characteristics of Atmospheric Organic Particulate Matter in Thermal Analysis, Environ. Sci. & Technol., 2002, 36 (4), 754-761.
Chemical speciation of organic aerosols at a molecular level: methods and applications
15.
M. Zheng, G. S. W. Hagler, L. Ke, M. H. Bergin, F. Wang, P. K. K. Louie, L. Salmon, D.W.M. Sin, J. Z. Yu, J. J. Schauer, Composition and Sources of Carbonaceous Aerosols at Three Contrasting Sites in Hong Kong. J. Geophys. Res. ¨CAtmosphere, 111, D20313, doi: 10.1029/2006JD007074.
16.
Y. C. Li, J. Z. Yu, Simultaneous Determination of Mono- and Di-carboxylic Acids, ¦Ø-Oxo-carboxylic Acids, Mid-chain Ketocarboxylic acids, and Aldehydes in Atmospheric Aerosol Samples, Environ. Sci. Technol. 2005, 39, 7616-7624.
17.
H. Yang, J. Z. Yu, S. S. H. Ho, J. H. Xu, W-S. Wu, C. H. Wan, X. D. Wang, X. R. Wang, L. S. Wang, The Chemical Composition of Inorganic and Carbonaceous Materials in PM2.5 in Nanjing, China, Atmos. Environ. 2005, 39 (20), 3735-3749.
18.
S. S. H. Ho and J. Z. Yu, In-Injection Port Thermal Desorption and Subsequent Gas Chromatography-Mass Spectrometric Analysis of Polycyclic Aromatic Hydrocarbons and n-Alkanes in Atmospheric Aerosol Samples, J. Chromatogr. A 2004, 1059 (1-2), 121-129.
19.
E. C. H. Wan, J. Z. Yu, Determination of Sugar Compounds in Atmospheric Aerosols by Liquid Chromatography Combined with Positive Electrospray Ionization Mass Spectrometry, J. Chromatogr. A 2006, 1107, 175-181.
Chemical characterization of aerosol nitrogen: methods and measurements
20.
Q. F. Li and J. Z. Yu, Determination of Total Aerosol Nitrogen by Thermal Evolution, Aerosol Sci. Technol., 2004, 38 (4), 382-390.
Characterization of ambient aerosols and toxic air pollutants in Hong Kong and in the Pearl River Delta Region
21.
G. S. W. Hagler, M. H. Bergin, L. G. Salmon, J. Z. Yu, E. C. H. Wan, M. Zheng, L. M. Zeng, C. S. Kiang, Y. H. Zhang, A. K. H. Lau, J. J. Schauer, Sources and Chemical Composition of Fine Particulate Matter in the Pearl River Delta Region of China, Atmos. Environ. 2006, 40, 3802-3815.
22.
Z. B. Yuan, A. K.H. Lau, H. Y. Zhang, J. Z. Yu, P. K. K. Louie, J. C. H. Fung, Identification and Spatiotemporal Variations of Dominant Pm10 sources over Hong Kong, Atmos. Environ. 2006, 40, 1803-1815.
23.
Z. B. Yuan, J. Z. Yu, A. K. H. Lau, P. K. K. Louie, J. C. H. Fung, Application of Positive Matrix Factorization in Estimating Aerosol Secondary Organic Carbon in Hong Kong and Its Relationship with Secondary Sulfate, Atmos. Chem. Phys. 2006, 6, 25-34.
24.
J. W. T. Tung, J. Z. Yu, A. K. H. Lau, P. K. K. Lau, Abundance and sources of ambient dioxins in Hong Kong: A review of dioxin measurements from 1997 to 2001, Chemosphere 2005, 59, 1387-1398.
25.
J. Z. Yu, J. W. T. Tung, A. W. M. Wu, A. K. H. Lau, P. K. ¨CK. Louie, J. C. H. Fung, Abundance and seasonal characteristics of elemental and organic carbon in Hong Kong, Atmos. Environ., 2004, 38 (10), 1511-1521.
Airborne carbonyl compounds: Method development and applications
26.
K. F. Ho, S. S. H. Ho, Y. Cheng, S. C. Lee, J. Z. Yu, Real-world emission of carbonyl compounds from a tunnel study in Hong Kong, Atmos. Environ. 2007, 41 (8), 1747-1758.
27.
S. S. H. Ho, J. Z. Yu, K. W. Chu, L. L. Yeung, Carbonyl Emissions from Commercial Cooking Sources in Hong Kong, J. Air Waste Manage. Assoc. 2006, 56 (8), 1091-1098.
28.
S. S. H. Ho and J. Z. Yu, Determination of Airborne Carbonyls: Comparison of a Thermal Desorption/GC Method with the Standard DNPH/HPLC Method, Environ. Sci. Technol. 2004, 38 (2), 862-870.
29.
S. S. H. Ho and J. Z. Yu, Concentrations of Formaldehyde and Other Carbonyls in Environments Affected by Incense Burning, J. Environ. Monitoring, 2002, 4, 728-733.
30.
S. S. H. Ho and J. Z. Yu, Feasibility of Collection and Analysis of Airborne Carbonyls by On-sorbent Derivatization and Thermal Desorption, Anal. Chem. 2002, 74, 1232-1240.
Previous publications
31.
M. Kalberer, J. Yu, D. R. Cocker, R. C. Flagan, and J. H. Seinfeld, Aerosol Formation in the Cyclohexene-Ozone System, Environ. Sci. Technol., 34, 2000, 4894-4901.
32.
Jianzhen Yu, David R. Cocker, Robert J. Griffin, Richard C. Flagan, and John H. Seinfeld, Gas-phase Ozone Oxidation of Monoterpenes: Gaseous and Particulate Products, J. Atmos. Chem., 34, 1999, 207-58.
33.
Jianzhen Yu, Robert J. Griffin, David R. Cocker, Richard C. Flagan, John H. Seinfeld, and Pierrette Blanchard, Observations of Gaseous and Particulate Products of Monoterpene Oxidation in Forest Atmospheres, Geophysical Research Letter, 26, 1999, 1145-8.
34.
Jianzhen Yu, Richard C. Flagan, and John H. Seinfeld, Identification of Products Containing -COOH, -OH, and-C=O in Atmospheric Oxidation of Hydrocarbons, Environmental Science& Technology, 32, 1998, 2357-72.
35.
Jianzhen Yu, Harvey E. Jeffries and Ken Sexton, Atmospheric Photooxidation of Alkylbenzenes: I. Carbonyl Product Analyses, Atmospheric Environment, 31, 1997, 2261-80.
36.
Jianzhen Yu and Harvey E. Jeffries, Atmospheric Photooxidation of Alkylbenzenes: II. Evidence of Epoxide Intermediates Formation, Atmospheric Environment, 31, 1997, 2281-7.
37.
Jianzhen Yu, Harvey E. Jeffries, and Richard M. Le Lacheur, Identifying Airborne Carbonyl Compounds in Isoprene Reaction Products by Their PFBHA Oximes Using Gas Chromatography/Ion Trap Mass Spectrometry, Environmental Science & Technology, 29, 1995, 1923-32.
38.
Jay R. Odum, Jianzhen Yu, and Richard M. Kamens, Modeling the Mass Transfer of Semivolatile Organics in Combustion Aerosols, Environmental Science & Technology, 28, 1994, 2278-85.
39.
Jianzhen Yu and Douglas G. Klarup, Extraction Kinetics of Copper, Zinc, Iron and Manganese from Contaminated Sediment Using Disodium Ethylenediaminetetraacetate, Water, Air and Soil Pollution, 75, 1994, 205-25.
[url]http://landsea.ust.hk/%7Echjianyu/index.html[/url]
[[i] 本帖最后由 Metalcarbene 于 2007-11-16 13:35 编辑 [/i]]
Dr Hong Kai WU
[attach]4446[/attach]Assistant Professor of Chemistry, Hong Kai WU (Ph.D, Harvard ; B.Sc., USTC )
E-mail: "chhkwu@ust.hk"
Tel: (852) 2358-7246; Fax: (852) 2358-1594
Research Interests:
Our research focuses on the interdisciplinary frontiers of microfluidics, bioanalytical science and materials chemistry. We use the technologies in MEMS, microfluidics, soft lithography, and surface chemistry to design and provide new tools for the applications and understanding of fundamentals in materials and biological sciences, including microfluidic chemical reactors, high throughput single-cell analysis and chemical separations.
Dr. Hongkai Wu graduated from the University of Science and Technology of China (USTC) in 1995. After receiving his B.S. degree also in USTC, he went to Harvard University in 1997 and obtained his Ph.D. degree there in Chemistry Department in 2002 under the supervision of Prof. George Whitesides. Then he joined Prof. Richard Zare's lab as a postdoc research assistant at Stanford University for 3 years before he took the position in Tsinghua University (Chemistry Department) as a professor in Nov. 2005.
In Feb. 2007, He was relocated to the Chemistry Department in the Hong Kong University of Science and Technology (HKUST) as an assistant professor.
[url]http://www-chem.ust.hk/faculty_Hong%20Kai%20Wu.html[/url] 不错，很好的学校！
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