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□-» Chirality in Drug Research(2006 Wiley-VCH)

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Title:  Chirality in Drug Research(2006 Wiley-VCH)
Division:  Medicinal / John Wiley & Son / 英文版
Author/Editor:  Dr. Eric Francotte, Prof. Wolfgang Lindner    Star:  
ISBN: 3527310762
Introduce Date:  2006年12月27日11:25 , Release Date:  2006年12月27日14:21
Introducer:  mjuchem , Rate: 9/408  
Format:  pdf(editorial)  Download 

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Description:

Chirality in Drug Research
Series: Methods and Principles in Medicinal Chemistry

Published Online: 11 Oct 2006

Editor(s): Dr. Eric Francotte, Prof. Wolfgang Lindner

Series Editor(s): Prof. Dr. Raimund Mannhold, Prof. Dr. Hugo Kubinyi, Prof. Dr. Gerd Folkers

Print ISBN-10: 3527310762    Online ISBN-10: 3527609431

Print ISBN-13: 9783527310760    Online ISBN-13: 9783527609437

DOI: 10.1002/3527609431

Copyright © 2006 Wiley-VCH Verlag GmbH & Co. KGaA

Front Matter (p I-XIX)
Summary  |  Full Text: PDF (Size: 109K)


Part none: Introduction
Chapter 1:
Chiral Drugs from a Historical Point of View (p 1-26)
Joseph Gal
Summary  |  Full Text: PDF (Size: 327K)


Part none: Synthesis
Chapter 2:
Stereoselective Synthesis of Drugs - An Industrial Perspective (p 27-65)
Hans-Jgen Federsel
Summary  |  Full Text: PDF (Size: 374K)


Chapter 3:
Aspects of Chirality in Natural Products Drug Discovery (p 67-94)
Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer
Summary  |  Full Text: PDF (Size: 348K)


Chapter 4:
Biotransformation Methods for Preparing Chiral Drugs and Drug Intermediates (p 95-123)
Michael Mler, Marcel Wubbolts
Summary  |  Full Text: PDF (Size: 325K)


Part none: Separations
Chapter 5:
Resolution of Chiral Drugs and Drug Intermediates by Crystallisation (p 125-154)
Kazuhiko Saigo, Kenichi Sakai
Summary  |  Full Text: PDF (Size: 485K)


Chapter 6:
Isolation and Production of Optically Pure Drugs by Enantioselective Chromatography (p 155-187)
Eric Francotte
Summary  |  Full Text: PDF (Size: 450K)


Chapter 7:
Stereoselective Chromatographic Methods for Drug Analysis (p 189-260)
Norbert M. Maier, Wolfgang Lindner
Summary  |  Full Text: PDF (Size: 815K)


Chapter 8:
Capillary Electrophoresis Coupled to Mass Spectrometry for Chiral Drugs Analysis (p 261-281)
Serge Rudaz, Jean-Luc Veuthey
Summary  |  Full Text: PDF (Size: 246K)


Chapter 9:
Powerful Chiral Molecular Tools for Preparation of Enantiopure Alcohols and Simultaneous Determination of Their Absolute Configurations by X-Ray Crystallography and/or 1H NMR Anisotropy Methods (p 283-321)
Nobuyuki Harada
Summary  |  Full Text: PDF (Size: 550K)


Chapter 10:
Keywords in Chirality Modeling: Molecular Modeling of Chirality - Software and Literature Research on Chirality in Modeling, Chirality in Docking, Chiral Ligand-Receptor Interaction and Symmetry (p 323-340)
Gerd Folkers, Mine Yarim, Pavel Pospisil
Summary  |  Full Text: PDF (Size: 174K)



Subject Index (p 341-351)
Summary  |  Full Text: PDF (Size: 73K)


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