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Title:
Antiviral Nucleosides - Chiral Synthesis and Chemotherapy |
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Division: Medicinal / Elsevier / 英文版 |
Author/Editor: C.K. Chu Star:  |
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ISBN: 0444513191 |
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Introduce Date: 2007年07月06日11:22 , Release Date: 2008年03月06日11:28 |
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Introducer: zrj , Rate: 2/249 |
| Format: pdf(editorial) Download |
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| Appraiser: moon_light | Grade: +1 | Reason: ( how to download? ) | | | Appraiser: whoknowme | Grade: -1 | Reason: ( 相关地址失效了,下载不了啊 ) | |
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| Description: |
Antiviral Nucleosides: Chiral Synthesis and Chemotherapy
Editor: C.K. Chu, College of Pharmacy, University of Georgia, Athens, GA, USA
Publisher: Elsevier
Publication Date: OCT-2003
Language: English
Number of Pages: 268 pages
Size: 11.40MB(PDF), 10.80MB(2 files RAR of PDF)
Price: $160.00
ISBN-10: 0444513191 (Hardcover)
ISBN-13: 9780444513199 (Hardcover)
Description
◇Up-to-date review on the chemistry and biology of nucleosides
◇Modern synthetic methodology
◇Comprehensive coverage of antiviral nucleosides
This book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past 10-15 years. It covers recently discovered nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also extensive reviews on their chiral synthesis.
Table of Contents
1. Recent Advances in Antiviral Nucleosides.
(G. Gumina, Y. Choi, C.K. Chu). Introduction. Structural features of nucleosides as antiviral agents. 2'-Deoxy nucleosides and related analogs. 2',3'-Dideoxy nucleosides and related analogues. 2',3'-Unsaturated nucleosides and related analogues. Nucleosides with a heterocyclic sugar ring moiety. 3- or 4-Membered ring nucleosides. Acyclonucleosides. Ribofuranosyl nucleosides. References.
2. Chiral synthesis of antiviral nucleosides from carbohydrate templates.
(G. Gumina, S. Olgen, C.K. Chu). Introduction. 4'-Thiofuranose nucleosides. Iso- and apio nucleosides. Oxathiolane and dioxolane nucleosides. Cyclopentyl carbocyclic nucleosides. Cyclopropyl carbocyclic nucleosides. C-Nucleosides. Fluorinated nucleosides. Acyclonucleosides. Miscellaneous nucleosides. References.
3. Oxathiolane and dioxolane nucleosides: Synthesis and antiviral activity. (G. Gumina, J.S. Cooperwood, C.K. Chu). Introduction. Oxathiolane nucleosides. Synthesis. Antiviral activity. Combination therapy. Dioxolane nucleosides. Synthesis. Antiviral activity. References.
Elsevier Link
http://www.elsevier.com/wps/find ... ription#description
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