From: jobs at ccl.net (do not send your application there!!!)
To: jobs at ccl.net
Date: Thu Nov 6 08:51:08 2008
Subject: 08.11.06 Research Investigator #26664 CADD
Bristol-Myers Squibb
www.bms.com
Position Description:The successful candidate will work with
multidisciplinary team comprised of computational chemists, chemists,
biologists, bioinformaticians and IT personnel. Identify correlations
between screening data from cell based and functional assays and small
molecule SAR. Predict and rationalize selectivity, potency, and function
of selected compounds using SAR. Develop binding models for compounds
with their respective targets. Develop pharmacophore models based on SAR.
Analyze data to identify SAR and target profiles.
Position Requirements: PhD in Computational Chemistry or related field.
2 years post doc or industrial experience preferred. Expertise in
small molecule drug design methods and QSAR. Familiarity with methods
for conformer analysis and optimization, de novo drug design,
pharmacophore modeling, molecular mechanics, quantum mechanics,
QM/MM, binding free energy prediction, and virtual screening.
Competency in programming in C/C++, in scripting languages such as
Perl and Python, and in statistics would be an advantage. An aptitude
and desire to learn and apply new techniques is expected. A basic
knowledge of medicinal chemistry and biology. Personal attributes of
integrity, creativity, problem solving, and strong work ethic. Excellent
communication skills.
To formally apply for this position, please go online to
http://www.bms.com/career/data/. You may search for the
position above by requisition number from the detailed search page.
Please apply to requisition #26664.
http://ccl.net/cca/jobs/joblist/mess0014594.shtml
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